Prostate-specific antigen, sexual behavior, and sexually transmitted infections in US men 40–59 years old, 2001–2004: a cross – sectional study

Table 2 PSA Concentration by Serum Antibody Testing among PSA Eligible Men (Age 40–49), NHANES 2001 – 2004

Variable	n	Predicted margin geometric mean PSA (ng/ml)	p-value	Predicted margin percent free PSA	p-value
Serum test for herpes simplex virus-2 exposure	737
Positive*	176	0.70 (0.63 to 0.77)	0.231	30.2 (28.1 to 32.4)	0.228
Negative or Indeterminate^†	561	0.74 (0.70 yo 0.79)	Reference	31.7 (30.4 to 33.0)	Reference
Serum test for T. pallidum exposure	737
Current^‡ or remote^§ infection	27	0.84 (0.66 to 1.06)	0.253	28.7 (22.7 to 34.7)	0.398
No infection^¶	710	0.73 (0.69 to 0.78)	Reference	31.5 (30.3 to 32.7)	Reference

* Serum has antibodies to HSV-2 gP-2 protein † Three results were indeterminate
‡ positive or indeterminate
• positive or indeterminate EIA test for T. pallidum antibodies, and rapid plasma reagin (RPR) ≥ 8
§positive EIA test, and 1 ≤ RPR ≤ 8 and a positive T. pallidum-particle agglutination (TP-PA)
¶ negative EIA test, or positive or indeterminate EIA test and RPR score 0–8 and negative TP-PA

ISSN: 1750-9378