Aberrant Epstein-Barr virus antibody patterns and chronic lymphocytic leukemia in a Spanish multicentric case-control study

Table 2 Odds ratios of chronic lymphocytic leukemia for aberrant EBV patterns

	N	N (%) ab_EBV positive	OR^a(95%CI)	P-value
Controls	157	17 (11%)	REF
Overall
All cases	150	34 (23%)	2.44 (1.29 to 4.62)	0.006
By Rai stages
CLL Rai 0	96	16 (17%)	1.67 (0.79 to 3.51)	0.18
CLL Rai I-IV (untreated^b)	37	11 (30%)	3.25 (1.35 to 7.82)	0.008
CLL Rai I-IV (treated^b)	16	7 (44%)	7.33 (2.33 to 23.06)	0.001

Ab_EBV: aberrant EBV pattern; CLL: Chronic lymphocytic leukemia; CI: confidence interval; N: Number; OR: Odds ratio; REF: reference group. ^a: Logistic regression for overall analysis on cases and controls, multinomial logistic regression otherwise. Odds ratios adjusted for age, sex and region. ^b: treated for CLL.

ISSN: 1750-9378