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Table 3 Mean log antibody measure (and standard error) for human herpesviruses 1–6 according to age at diagnosis, sex and other socio-demographic factors.

From: Antibodies against six human herpesviruses in relation to seven cancers in black South Africans: A case control study

Risk factor   Virus
   HSV-1 HSV-2 VZV EBV-EBNA CMV HHV-6
Age <20 1.55 (0.11) -0.19 (0.20) 1.06 (0.12) 1.52 (0.15) 1.79 (0.21) 0.64 (0.15)
  20–39 1.61 (0.04) 0.25 (0.08) 1.06 (0.05) 1.44 (0.07) 2.19 (0.12) 0.70 (0.06)
  40–59 1.61 (0.04) 0.36 (0.07) 1.07 (0.05) 1.40 (0.07) 2.26 (0.07) 0.74 (0.06)
  60+ 1.60 (0.05) 0.48 (0.08) 1.11 (0.06) 1.47 (0.07) 2.41 (0.09) 0.66 (0.05)
p-value   0.92 0.003 0.41 0.77 0.006 0.52
Sex Males 1.59 (0.05) 0.05 (0.08) 1.03 (0.06) 1.43 (0.07) 1.98 (0.09) 0.59 (0.06)
  Females 1.60 (0.05) 0.40 (0.08) 1.11 (0.06) 1.48 (0.07) 2.34 (0.10) 0.78 (0.06)
p-value   0.91 <0.0001 0.09 0.44 <0.0001 0.0002
Smoking Never 1.60 (0.04) 0.21 (0.08) 1.03 (0.05) 1.45 (0.07) 2.16 (0.09) 0.67 (0.06)
  Ever 1.59 (0.05) 0.24 (0.09) 1.11 (0.06) 1.46 (0.08) 2.17 (0.10) 0.70 (0.06)
p-value   0.91 0.56 0.07 0.96 0.94 0.34
Education < Grade 3 1.59 (0.05) 0.30 (0.09) 1.10 (0.06) 1.41 (0.08) 2.18 (0.10) 0.74 (0.07)
  Grade 3–7 1.64 (0.05) 0.24 (0.08) 1.09 (0.05) 1.47 (0.07) 2.13 (0.09) 0.69 (0.06)
  Grade 8+ 1.55 (0.05) 0.14 (0.09) 1.04 (0.06) 1.49 (0.08) 2.18 (0.10) 0.64 (0.07)
p-value   0.53 0.09 0.26 0.18 0.99 0.14
Area of birth Urban 1.61 (0.05) 0.28 (0.09) 1.10 (0.06) 1.46 (0.07) 2.14 (0.10) 0.70 (0.06)
  Rural 1.57 (0.04) 0.18 (0.08) 1.05 (0.05) 1.45 (0.07) 2.19 (0.09) 0.67 (0.07)
p-value   0.29 0.13 0.16 0.67 0.48 0.45
Area living Urban 1.59 (0.04) 0.19 (0.07) 1.08 (0.05) 1.45 (0.07) 2.17 (0.09) 0.71 (0.06)
  Rural 1.59 (0.05) 0.27 (0.09) 1.07 (0.06) 1.46 (0.08) 2.15 (0.11) 0.67 (0.06)
p-value   0.99 0.35 0.83 0.76 0.85 0.53
HIV +ve 1.53 (0.06) 0.27 (0.11) 1.12 (0.07) 1.43 (0.09) 2.22 (0.12) 0.71 (0.08)
  -ve 1.66 (0.04) 0.18 (0.07) 1.02 (0.05) 1.48 (0.06) 2.11 (0.08) 0.67 (0.05)
p-value   0.03 0.35 0.10 0.52 0.34 0.66
No. of 0–2 1.60 (0.05) 0.12 (0.08) 1.02 (0.06) 1.47 (0.07) 2.12 (0.09) 0.64 (0.06)
sexual 3–5 1.58 (0.05) 0.25 (0.08) 1.05 (0.06) 1.41 (0.07) 2.18 (0.09) 0.75 (0.06)
partners 6+ 1.60 (0.05) 0.31 (0.09) 1.15 (0.06) 1.49 (0.08) 2.19 (0.11) 0.67 (0.07)
p-value   0.96 0.01 0.03 0.96 0.34 0.26
Marital Single 1.58 (0.04) 0.06 (0.08) 1.04 (0.05) 1.45 (0.07) 2.03 (0.09) 0.65 (0.06)
status Married 1.62 (0.05) 0.22 (0.08) 1.11 (0.05) 1.43 (0.07) 2.16 (0.09) 0.67 (0.06)
  Widowed 1.59 (0.06) 0.20 (0.11) 1.04 (0.07) 1.41 (0.09) 2.17 (0.12) 0.66 (0.08)
  Separated 1.58 (0.07) 0.42 (0.12) 1.10 (0.08) 1.54 (0.10) 2.29 (0.14) 0.77 (0.09)
p-value   0.64 0.005 0.45 0.52 0.26 0.34
  1. Multivariate analysis of variance excluding patients with multiple myeloma and adjusted for all factors above plus disease group, plate and day of assay. P-values are for trend tests where appropriate and otherwise for heterogeneity.
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