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  3. Cervical cancer is the greater cause of cancer death in women in many developing countries. Persistent infection with human papilloma virus (HPV), primarily high risk types 16 and 18, is recognized as a causal...

    Authors: Mohammadreza Haghshenas, Tahereh Golini-moghaddam, Alireza Rafiei, Omid Emadeian, Ahmad Shykhpour and G Hossein Ashrafi
    Citation: Infectious Agents and Cancer 2013 8:20
    Content type: Research Article Published on:

  4. Worldwide, cancers of the urinary bladder are well known to be associated with environmental chemical carcinogens such as smoking and occupational exposure to polycyclic aromatic hydrocarbons. These cancers ar...

    Authors: Peter Fabian Rambau, Philipo L Chalya and Kahima Jackson
    Citation: Infectious Agents and Cancer 2013 8:19
    Content type: Research Article Published on:

  5. In HIV-infected populations in developed countries, the most recent published cancer incidence trend analyses are only updated through 2008. We assessed changes in the distribution of cancer types and incidenc...

    Authors: Elizabeth L Yanik, Kristen Tamburro, Joseph J Eron, Blossom Damania, Sonia Napravnik and Dirk P Dittmer
    Citation: Infectious Agents and Cancer 2013 8:18
    Content type: Research Article Published on:

  6. Lung cancer is an important etiology of malignant mortality worldwide with global statistics indicating over 1 million deaths annually. Although there have been advances in cytotoxic chemotherapy, the prognosi...

    Authors: Syed Hassan Abbas Naqvi, Syed Hassan Shiraz Naqvi, Muhammad Yasin Bandukda and Syed Mumtaz Ali Naqvi
    Citation: Infectious Agents and Cancer 2013 8:17
    Content type: Letter to the Editor Published on:

  10. Exploring the presence and role of human papillomavirus (HPV) in head and neck cancer (HNC) is a necessary step to evaluate the potential impact of HPV prophylactic vaccines.

    Authors: Cathy Ndiaye, Laia Alemany, Yankhoba Diop, Nafissatou Ndiaye, Marie-Joseph Diémé, Sara Tous, Jo Ellen Klaustermeier, Maria Alejo, Xavier Castellsagué, F Xavier Bosch, Helen Trottier and Silvia de Sanjosé
    Citation: Infectious Agents and Cancer 2013 8:14
    Content type: Short report Published on:

  11. c-Met is a receptor tyrosine kinase that encodes protein such as hepatocyte growth factor receptor (HGFR). Inappropriate activity of c-Met can cause wide variety of carcinomas. c-Met inhibitor are relatively n...

    Authors: Anum Mughal, Hafiz Muhammad Aslam, Asfandyar Sheikh, Agha Muhammad Hammad Khan and Shafaq Saleem
    Citation: Infectious Agents and Cancer 2013 8:13
    Content type: Letter to the Editor Published on:

  12. It has been hypothesized that human cytomegalovirus (HCMV) may be associated with breast cancer progression. However, the role of HCMV infection in breast cancer remains controversial. We aimed to assess wheth...

    Authors: Dolores Utrera-Barillas, Hilda-Alicia Valdez-Salazar, David Gómez-Rangel, Isabel Alvarado-Cabrero, Penélope Aguilera, Alejandro Gómez-Delgado and Martha-Eugenia Ruiz-Tachiquin
    Citation: Infectious Agents and Cancer 2013 8:12
    Content type: Short report Published on:

  15. The purpose of this study was to determine if any relationship exists between expression of COX2 and iNOS markers and urinary schistosomiasis in bladder cancers.

    Authors: Hassan Elsiddig Hassan, Ahmed Abdel Badie Mohamed, Amel Omer Bakhiet and Hussain Gadelkarim Ahmed
    Citation: Infectious Agents and Cancer 2013 8:9
    Content type: Research article Published on:

  16. The obligate intracellular protozoan parasite Toxoplasma gondii infects humans and other warm-blooded animals and establishes a chronic infection in the central nervous system after invasion. Studies showing a po...

    Authors: Sivasakthivel Thirugnanam, Namita Rout and Munirathinam Gnanasekar
    Citation: Infectious Agents and Cancer 2013 8:8
    Content type: Hypothesis Published on:

  18. The rationale behind current worldwide human papilloma virus (HPV) vaccination programs starts from two basic premises, 1) that HPV vaccines will prevent cervical cancers and save lives and, 2) have no risk of...

    Authors: Lucija Tomljenovic, Judy Wilyman, Eva Vanamee, Toni Bark and Christopher A Shaw
    Citation: Infectious Agents and Cancer 2013 8:6
    Content type: Letter to the Editor Published on:

  19. Only a small portion of HPV 16 infections persist and can lead to cervical intraepithelial lesions and cancer. Factors that favour HPV persistence versus clearance are still poorly understood, but several stud...

    Authors: Iris Cornet, Tarik Gheit, Gary M Clifford, Jean-Damien Combes, Véronique Dalstein, Silvia Franceschi, Massimo Tommasino and Christine Clavel
    Citation: Infectious Agents and Cancer 2013 8:4
    Content type: Research article Published on:

  20. Kaposi sarcoma-associated herpesvirus (KSHV) seropositivity is associated with sexual, environmental, and socioeconomic exposures. Whether these characteristics are independent risk factors is uncertain becaus...

    Authors: Joanne T Chang, Fatma M Shebl, Ruth M Pfeiffer, Benon Biryahwaho, Barry I Graubard and Sam M Mbulaiteye
    Citation: Infectious Agents and Cancer 2013 8:3
    Content type: Research article Published on:

  21. Human papillomavirus (HPV) infection accounts for about 40-50% of all cases of penile carcinoma suggesting that other factors, including host genetic status, are involved in neoplastic transformation. In this ...

    Authors: Clorinda Annunziata, Luigi Buonaguro, Simona Losito, Franco M Buonaguro and Maria Lina Tornesello
    Citation: Infectious Agents and Cancer 2013 8:2
    Content type: Research article Published on:

  22. Bovine papillomaviruses (BPVs) are oncogenic DNA viruses, which mainly induce benign lesions of cutaneous and/or mucosal epithelia in cattle. Thirteen (BPV 1–13) different viral genotypes have been characteriz...

    Authors: Annunziata Corteggio, Gennaro Altamura, Franco Roperto and Giuseppe Borzacchiello
    Citation: Infectious Agents and Cancer 2013 8:1
    Content type: Review Published on:

  23. Information on human papillomavirus (HPV) type distribution is necessary to evaluate the potential impact of current and future HPV vaccines. We estimated the relative contribution (RC) to invasive cervical ca...

    Authors: Beatriz Serrano, Laia Alemany, Sara Tous, Laia Bruni, Gary M Clifford, Thomas Weiss, Francesc Xavier Bosch and Silvia de Sanjosé
    Citation: Infectious Agents and Cancer 2012 7:38
    Content type: Research article Published on:

  24. Human Papilloma Virus (HPV) is a major leading cause of Human Cancer. Through the HPV Prevention series we would like to highlight the quality and the breadth of the research being carried out on the Control a...

    Authors: Silvia de Sanjosé
    Citation: Infectious Agents and Cancer 2012 7:37
    Content type: Editorial Published on:

  25. Nasopharyngeal carcinomas (NPC) are consistently associated with the Epstein-Barr virus (EBV). Though NPCs are more radiosensitive and chemosensitive than other tumors of the upper aero-digestive tract, many t...

    Authors: Benjamin Vérillaud, Mélanie Gressette, Yannis Morel, Carine Paturel, Philippe Herman, Kwok Wai Lo, Sai Wah Tsao, Michel Wassef, Anne-Sophie Jimenez-Pailhes and Pierre Busson
    Citation: Infectious Agents and Cancer 2012 7:36
    Content type: Research article Published on:

  26. Since the late 1990s, infectious agents have been thought to play a role in the pathogenesis of approximately 15% of cancers. It is now widely accepted that infection of stomach tissue with the bacteria Helicobac...

    Authors: Kenneth Alibek, Nargis Karatayeva and Ildar Bekniyazov
    Citation: Infectious Agents and Cancer 2012 7:35
    Content type: Review Published on:

  27. Human Papillomavirus (HPV) in cervical epithelium has been identified as the main etiological factor in the developing of Cervical Cancer (CC), which has recently become a public health problem in Mexico. This...

    Authors: Raúl Peralta-Rodríguez, Pablo Romero-Morelos, Vanessa Villegas-Ruíz, Mónica Mendoza-Rodríguez, Keiko Taniguchi-Ponciano, Beatriz González-Yebra, Daniel Marrero-Rodríguez and Mauricio Salcedo
    Citation: Infectious Agents and Cancer 2012 7:34
    Content type: Research article Published on:

  28. Recent clinical and pre-clinical data demonstrate that adjuvant antimicrobial therapy is beneficial in cancer treatment. There could be several reasons for this effect, which include treating cancer associated...

    Authors: Kenneth Alibek, Aliya Bekmurzayeva, Assel Mussabekova and Bolat Sultankulov
    Citation: Infectious Agents and Cancer 2012 7:33
    Content type: Review Published on:

  29. Women with Human Papilloma Virus (HPV) persistence are characterized by high levels of IL-10 at cervix. We have determined whether polymorphisms of IL-10 gene promoter might be associated with increased risk o...

    Authors: Kirvis Torres-Poveda, Ana I Burguete-García, Miguel Cruz, Gabriela A Martínez-Nava, Margarita Bahena-Román, Esmeralda Ortíz-Flores, Abrahan Ramírez-González, Guillermina López-Estrada, Karina Delgado-Romero and Vicente Madrid-Marina
    Citation: Infectious Agents and Cancer 2012 7:32
    Content type: Research article Published on:

  30. Infectious etiology in lymphoproliferative diseases has always been suspected. The pathogenic roles of human herpesvirus-6 (HHV-6) in acute leukemia have been of great interest. Discordant results to establish...

    Authors: Nefzi Faten, Gautheret-Dejean Agnès, Ben Fredj Nadia, Abid Ben Salem Nabil, Zaier Monia, Khelif Abderrahim, Agut Henri, Feki Salma and Aouni Mahjoub
    Citation: Infectious Agents and Cancer 2012 7:31
    Content type: Research article Published on:

  31. The major cause of cervical intraepithelial neoplasia (CIN) is persistent infection with human papillomavirus (HPV). Most CIN grade 2 and 3 lesions are treated with cone excision, although a substantial propor...

    Authors: Ane Cecilie Munk, Irene Tveiterås Øvestad, Einar Gudlaugsson, Kjell Løvslett, Bent Fiane, Bianca van Diermen-Hidle, Arnold-Jan Kruse, Ivar Skaland, Emiel AM Janssen and Jan PA Baak
    Citation: Infectious Agents and Cancer 2012 7:30
    Content type: Research article Published on:

  32. The Hedgehog (Hh) proteins comprise a group of secreted proteins that regulate cell growth, differentiation and survival. Inappropriate activation of the Hh signaling pathway has been implicated in the develop...

    Authors: Asfandyar Sheikh, Arsalan Ahmad Alvi, Hafiz Muhammad Aslam and Abdul Haseeb
    Citation: Infectious Agents and Cancer 2012 7:29
    Content type: Letter to the Editor Published on:

  33. The epidemic of HIV in sub-Saharan Africa varies significantly across countries in the region with high prevalence in Southern Africa and Nigeria. Cancer is increasingly identified as a complication of HIV inf...

    Authors: Elima Jedy-Agba and Clement Adebamowo
    Citation: Infectious Agents and Cancer 2012 7:28
    Content type: Research article Published on:

  34. Hepatitis B virus (HBV) encodes an oncogenic factor, HBx, which is a multifunctional protein that can induce dysfunctional regulation of signaling pathways, transcription, and cell cycle progression, among oth...

    Authors: Sergio Hernández, Mauricio Venegas, Javier Brahm and Rodrigo A Villanueva
    Citation: Infectious Agents and Cancer 2012 7:27
    Content type: Research article Published on:

  35. The aim of this study is to describe the prevalence of HPV types in invasive cervical cancers in Italy from 1996 to 2008.

    Authors: Paolo Giorgi Rossi, Mario Sideri, Francesca Maria Carozzi, Amina Vocaturo, Franco Maria Buonaguro, Maria Lina Tornesello, Elena Burroni, Luciano Mariani, Sara Boveri, Leandra Maria Zaffina and Francesco Chini
    Citation: Infectious Agents and Cancer 2012 7:26
    Content type: Research article Published on:

  36. An increasing incidence of malignant mesothelioma (MM) cases in patients with low levels of asbestos exposure suggests the interference of alternative cofactors. SV40 infection was detected, as co-morbidity fa...

    Authors: Martina Girardelli, Iva Maestri, Rosa R Rinaldi, Mauro Tognon, Renzo Boldorini, Massimo Bovenzi, Sergio Crovella and Manola Comar
    Citation: Infectious Agents and Cancer 2012 7:25
    Content type: Research Article Published on:

  37. This article reviews the existing realities in Uganda to identify opportunities and potential obstacles of providing universal routine HPV vaccination to young adolescent girls. Cervical cancer is a public hea...

    Authors: Cecily Banura, Florence M Mirembe, Anne R Katahoire, Proscovia B Namujju and Edward K Mbidde
    Citation: Infectious Agents and Cancer 2012 7:24
    Content type: Review Published on:

  38. This is a report on some of the research activities currently ongoing in Italy as outlined at the “Viruses and solid tumors” meeting jointly organized by the Oncology Sections of IRCCS Policlinico “San Matteo”...

    Authors: Vittorio Perfetti, Mattia Ricotti, Franco Buonaguro, Umberto Tirelli and Paolo Pedrazzoli
    Citation: Infectious Agents and Cancer 2012 7:23
    Content type: Meeting Report Published on:

  39. Mice latently infected with murine gammaherpesvirus 68 (HV-68) and transplanted with 4 T1 breast cancer cells developed exacerbated metastatic lesions when compared to controls. The mechanisms responsible for ...

    Authors: Daniel A Nelson, Vinita S Chauhan, Melanie D Tolbert and Kenneth L Bost
    Citation: Infectious Agents and Cancer 2012 7:22
    Content type: Research Article Published on:

  40. EBV DNA is found within the malignant cells of 10% of gastric cancers. Modern molecular technology facilitates identification of virus-related biochemical effects that could assist in early diagnosis and disea...

    Authors: Weihua Tang, Douglas R Morgan, Michael O Meyers, Ricardo L Dominguez, Enrique Martinez, Kennichi Kakudo, Pei Fen Kuan, Natalie Banet, Hind Muallem, Kimberly Woodward, Olga Speck and Margaret L Gulley
    Citation: Infectious Agents and Cancer 2012 7:21
    Content type: Research Article Published on:

  42. Bladder cancer is a common malignancy in Egypt. A history of urinary tract infection can be considered as a risk factor for bladder cancer. Escherichia coli (E. coli) infection is responsible for 70% of urinary t...

    Authors: Hala El-Mosalamy, Tarek M Salman, Abeer M Ashmawey and Nada Osama
    Citation: Infectious Agents and Cancer 2012 7:19
    Content type: Research article Published on:

  44. This study examined whether there is a positive correlation existed between cervical and oral High Risk-Human Papilloma Viruses (HR-HPV) types 16, 18 infections in patients with clinically confirmed cervical l...

    Authors: Abdelbaset Mohamed Elasbali, El Din Afra Hassan Saad, Abdallah Rania Abdeen Hussein and Ahmed Hussain Gadelkarim
    Citation: Infectious Agents and Cancer 2012 7:17
    Content type: Research article Published on:

  45. Galectin-9 is a mammalian lectin which possesses immunosuppressive properties. Excessive production of galectin-9 has been reported in two types of human virus-associated diseases chronic hepatitis C and nasop...

    Authors: Clément Barjon, Toshiro Niki, Benjamin Vérillaud, Paule Opolon, Pierre Bedossa, Mitsuomi Hirashima, Stéphanie Blanchin, Michel Wassef, Hugo R Rosen, Anne-Sophie Jimenez, Ming Wei and Pierre Busson
    Citation: Infectious Agents and Cancer 2012 7:16
    Content type: Research article Published on:

  46. Liver disease is the second cause of death among HIV patients receiving highly active antiretroviral therapy (HAART) in Europe. HIV patients have a high prevalence of chronic HBV (6–10%) and HCV (33%) co-infec...

    Authors: Pasquale De Nardo, Magdalena Viscione, Angela Corpolongo, Rita Bellagamba, Giovanni Vennarecci, Giuseppe Maria Ettorre, Elisa Gentilotti, Chiara Tommasi and Emanuele Nicastri
    Citation: Infectious Agents and Cancer 2012 7:15
    Content type: Short report Published on:

  47. Compounds that can act as agonists for toll-like receptors (TLRs) may be promising candidates for the development of drugs against infectious diseases and cancer. The present study aimed to characterize the im...

    Authors: Wagner J Fávaro, Odilon S Nunes, Fabio RF Seiva, Iseu S Nunes, Lisa K Woolhiser, Nelson Durán and Anne J Lenaerts
    Citation: Infectious Agents and Cancer 2012 7:14
    Content type: Research article Published on:

  48. Head & Neck Cancer (HNC) is one of the most common malignancies worldwide and among oral neoplasias about 90-92% are squamous cell carcinomas (OSCC). Alcohol and tobacco consumption have been recognized as the...

    Authors: Chloé Bertolus, Patrick Goudot, Antoine Gessain and Nicolas Berthet
    Citation: Infectious Agents and Cancer 2012 7:13
    Content type: Commentary Published on:

  49. Most infections with human papillomavirus (HPV) are resolved without clinical intervention, but a minority evolves into chronic lesions of distinct grades, including cervical-uterine cancer. It is known that i...

    Authors: Jorge Hernández-Montes, Leticia Rocha-Zavaleta, Alberto Monroy-García, Benny Weiss-Steider, María del Carmen Zaragoza-Ortega, Fernando Cruz-Talonia, Omar Cruz y Cruz, Laura Bonifaz-Alfonso, Adriana Karina Chávez-Rueda, Martha Patricia Rojo-Aguilar, María Victoria Legorreta-Haquet and María de Lourdes Mora-García
    Citation: Infectious Agents and Cancer 2012 7:12
    Content type: Research article Published on:

  50. Controversy exists as to the ability of human gammaherpesviruses to cause or exacerbate breast cancer disease in patients. The difficulty in conducting definitive human studies can be over come by investigatin...

    Authors: Vinita S Chauhan, Daniel A Nelson, Lopamudra Das Roy, Pinku Mukherjee and Kenneth L Bost
    Citation: Infectious Agents and Cancer 2012 7:11
    Content type: Research article Published on:

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