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  3. The association between high risk human papillomaviruses (HPV) and cervical cancer has been firmly established. HPV genome is present in nearly all cases of cervical cancer and detection of viral DNA could the...

    Authors: Marianna Tortora, Clorinda Annunziata, Giuseppina Liguori, Simona Losito, Gerardo Botti, Stefano Greggi, Luigi Buonaguro, Franco M. Buonaguro and Maria Lina Tornesello
    Citation: Infectious Agents and Cancer 2016 11:22
    Content type: Research Article Published on:

  4. Human papillomavirus (HPV) prevalence in head and neck squamous cell carcinomas (HNSCC) diverges geographically. The reliability of using p16INK4a expression as a marker of viral infection is controversial in HNS...

    Authors: Julio C. Betiol, Laura Sichero, Henrique O. de Olival Costa, Leandro L. de Matos, Maria A. Andreoli, Silvaneide Ferreira, Sheila F. Faraj, Evandro S. de Mello, João S. Sobrinho, Lenine G. Brandão, Claudio R. Cernea, Marco A. Kulcsar, Fabio R. Pinto, Antonio J. Gonçalves, Marcelo B. Menezes, Leonardo Silva…
    Citation: Infectious Agents and Cancer 2016 11:20
    Content type: Research Article Published on:

  5. Human papilloma virus (HPV) is a known causative factor in oropharyngeal squamous cell cancer (OPC). In this prospective study, we sought to define the risk of HPV transmission between OPC patients and their s...

    Authors: Anne S. Tsao, Vassiliki Papadimitrakopoulou, Heather Lin, Ming Guo, J. Jack Lee, F. Christopher Holsinger, Waun Ki Hong and Erich M. Sturgis
    Citation: Infectious Agents and Cancer 2016 11:21
    Content type: Research Article Published on:

  6. This article evaluates a single institute’s radiotherapy management of OSSN, a previously regarded as rare malignancy, for possible future development of strategies to clearly define the role of adjuvant radio...

    Authors: Ntokozo Ndlovu, Sandra Ndarukwa, Webster Kadzatsa and Simbarashe Rusakaniko
    Citation: Infectious Agents and Cancer 2016 11:18
    Content type: Research Article Published on:

  7. p16INK4A expression has been used as a surrogate marker for human papillomavirus (HPV) infection in cervical cancer and head and neck cancer. p53 has also been reported as a feasible marker to identify HPV-positi...

    Authors: Lianghai Wang, Jing Li, Jun Hou, Man Li, Xiaobin Cui, Shugang Li, Xiaodan Yu, Zhiyu Zhang, Weihua Liang, Jinfang Jiang, Lijuan Pang, Yunzhao Chen, Jin Zhao and Feng Li
    Citation: Infectious Agents and Cancer 2016 11:19
    Content type: Research Article Published on:

  8. HPV is the major etiological factor in the causal pathway for cervical cancer, which is the leading cancer among women in sub-Saharan Africa. HIV is associated with a higher prevalence and a broader range of h...

    Authors: Sonia Simone Menon, Rodolfo Rossi, Ronald Harebottle, Hillary Mabeya and Davy vanden Broeck
    Citation: Infectious Agents and Cancer 2016 11:17
    Content type: Research Article Published on:

  9. The association of human papillomavirus (HPV) types to neoplastic lesions increase as a function of their oncogenicity and the duration of the infection since lesion severity progresses from low-grade to high-...

    Authors: Raúl DelaRosa-Martínez, Mireya Sánchez-Garza and Rubén López-Revilla
    Citation: Infectious Agents and Cancer 2016 11:16
    Content type: Research Article Published on:

  10. Organized cervical cancer screening services are presently lacking in Nigeria contributing to late presentation and diagnosis of invasive cervical cancer cases (ICCs) at advanced stages in most gynecologic uni...

    Authors: Jonah Musa, Joseph Nankat, Chad J. Achenbach, Iornum H. Shambe, Babafemi O. Taiwo, Barnabas Mandong, Patrick H. Daru, Robert L. Murphy and Atiene S. Sagay
    Citation: Infectious Agents and Cancer 2016 11:15
    Content type: Research Article Published on:

  11. Most women in developing countries have never attended cervical screening programmes and often little information exists on type-specific human papillomavirus (HPV) prevalence among these populations. Self-sam...

    Authors: Pierre Vassilakos, Rosa Catarino, Stephanie Bougel, Maria Munoz, Caroline Benski, Ulrike Meyer-Hamme, Jeromine Jinoro, Josea Lea Heriniainasolo and Patrick Petignat
    Citation: Infectious Agents and Cancer 2016 11:13
    Content type: Research Article Published on:

  13. We earlier proposed a genetic model for gallbladder carcinogenesis and its dissemination cascade. However, the association of gallbladder cancer and ‘inflammatory stimulus’ to drive the initial cascade in the ...

    Authors: Prajish Iyer, Savio George Barreto, Bikram Sahoo, Pratik Chandrani, Mukta R. Ramadwar, Shailesh V. Shrikhande and Amit Dutt
    Citation: Infectious Agents and Cancer 2016 11:12
    Content type: Short Report Published on:

  15. Insulin resistance is considered to be an important factor in the progression of fibrosis and the enhancement of the risk of hepatocellular carcinoma (HCC) for chronic hepatitis C patients. The aim of this stu...

    Authors: Takeo Hayashi, Eiichi Ogawa, Norihiro Furusyo, Masayuki Murata and Jun Hayashi
    Citation: Infectious Agents and Cancer 2016 11:9
    Content type: Research Article Published on:

  16. The association of human papillomavirus (HPV) with cervical cancer is well established.

    Authors: Mohamed A. Youssef, Lobna Abdelsalam, Reem Abdelhameed Harfoush, Iman Mamdouh Talaat, Eman Elkattan, Abeer Mohey, Rana M. A. Abdella, Marwa Salah Farhan, Hany Ahmed Foad, Abeer Mostafa Elsayed, Naglaa A. Elkinaai, Doaa Ghaith, Mohamed Elsayed Rashed, Mohamed Abd-El Ghafar, Yasser Khamis and Ahmed N. Hosni
    Citation: Infectious Agents and Cancer 2016 11:6
    Content type: Research Article Published on:

  17. The editors of Infectious Agents and Cancer would like to thank all our reviewers who have contributed their time and expertise to the journal in Volume 10 (2015).

    Authors: Franco M. Buonaguro, Sam M. Mbulaiteye and Maria Lina Tornesello
    Citation: Infectious Agents and Cancer 2016 11:10
    Content type: Reviewer acknowledgement Published on:

  18. Human herpesvirus-8 (HHV-8), the etiologic agent of Kaposi sarcoma (KS), establishes lifelong latent infection with periodic lytic replication (“shedding”) at mucosal sites, especially the oropharynx. Patterns...

    Authors: Rachel A. Bender Ignacio, Jason D. Goldman, Amalia S. Magaret, Stacy Selke, Meei-Li Huang, Soren Gantt, Christine Johnston, Warren T. Phipps, Joshua T. Schiffer, Richard A. Zuckerman, R. Scott McClelland, Connie Celum, Larry Corey, Anna Wald and Corey Casper
    Citation: Infectious Agents and Cancer 2016 11:7
    Content type: Research Article Published on:

  20. We present here a case of immune reconstitution inflammatory syndrome associated with Kaposi’s sarcoma (KS-IRIS) developed in an AIDS patient two months after initiation of antiretroviral therapy (ART). Baseli...

    Authors: Anna Maria Cattelan, Adriana Mattiolo, Angela Grassi, Maria Assunta Piano, Lolita Sasset, Marco Trevenzoli, Paola Zanovello and Maria Luisa Calabrò
    Citation: Infectious Agents and Cancer 2016 11:5
    Content type: Short Report Published on:

  21. Human Papillomavirus (HPV) infections have been shown to be a necessary risk factor for the development of cervical cancer. However, HPV genotype distribution varies geographically, both in type and relative p...

    Authors: A. K. Awua, S. T. Sackey, Y. D. Osei, R. H. Asmah and E. K. Wiredu
    Citation: Infectious Agents and Cancer 2016 11:4
    Content type: Research Article Published on:

  22. Mounting evidence suggests a causal relationship between specific bacterial infections and the development of certain malignancies. However, the possible role of the keystone periodontal pathogen, Porphyromonas g...

    Authors: Shegan Gao, Shuoguo Li, Zhikun Ma, Shuo Liang, Tanyou Shan, Mengxi Zhang, Xiaojuan Zhu, Pengfei Zhang, Gang Liu, Fuyou Zhou, Xiang Yuan, Ruinuo Jia, Jan Potempa, David A. Scott, Richard J. Lamont, Huizhi Wang…
    Citation: Infectious Agents and Cancer 2016 11:3
    Content type: Research Article Published on:

  23. Cervical cancer is one of the most common tumors affecting women with a disproportionate mortality occurring in developing countries. Despite the high prevalence of cervical cancer and cervical neoplasia in Ga...

    Authors: Samira Zoa Assoumou, Angelique Ndjoyi Mbiguino, Barthelemy Mabika Mabika, Sidonie Nguizi Ogoula, Mohammed El Mzibri, Abdelkrim Khattabi and My Mustapha Ennaji
    Citation: Infectious Agents and Cancer 2016 11:2
    Content type: Research Article Published on:

  24. Human Papillomavirus (HPV) is well known pathogen that can cause benign and malignant tumors in humans, yet there is very little information regarding HPV types prevalent in Pakistan.

    Authors: Abdullah Abdullah, Muhammad Qasim, Muhammad Shafiq, Muhammad Ijaz, Shamsa Parveen, Shahnaz Murtaza, Qamar Javed, Salman Akbar Malik, Shahida Husain Tarar, Sajid Mehmood, Abdul Sami, Syed Muhammad Saqlan Naqvi and Muhammad Zeeshan Hyder
    Citation: Infectious Agents and Cancer 2016 11:1
    Content type: Research Article Published on:

  25. According to the World Health Organisation (WHO), deaths from non-communicable diseases (NCDs) will increase globally, with the largest increase being on the African continent. On our continent, projections ha...

    Authors: D. C. Stefan, N. Masalu, L. Ngendahayo, D. Amadori, M. Botteghi, M. Mendy, N. A. Othieno-Aabinya, T. Ngoma, F. Asirwa, O. Balogun, W. Ngwa, E. Vuhahula and A Adesina
    Citation: Infectious Agents and Cancer 2015 10:48
    Content type: Meeting Report Published on:

  26. Simple epithelial keratins appear early during embryonic development and are expressed in non-stratified, ductal and pseudo-stratified epithelial tissues. CK19, the lowest molecular weight keratin, is also exp...

    Authors: Angela Santoro, Giuseppe Pannone, Rossella Ninivaggi, Massimo Petruzzi, Andrea Santarelli, Giuseppe Maria Russo, Silvia Lepore, Michele Pietrafesa, Ilaria Laurenzana, Rosalia Leonardi, Paolo Bucci, Maria Iole Natalicchio, Alberta Lucchese, Silvana Papagerakis and Pantaleo Bufo
    Citation: Infectious Agents and Cancer 2015 10:46
    Content type: Research Article Published on:

  28. Data on Human PapillomaVirus (HPV) infection are scarce in Morocco. The objective of the study was to determine the prevalence of HPV and cervical cytology abnormalities in women from the Souss area, Morocco.

    Authors: Essaada Belglaiaa, Hicham Elannaz, Bouchra Mouaouya, Mohamed Aksim, Mariette Mercier, Jean-Luc Prétet, Said Chouham and Christiane Mougin
    Citation: Infectious Agents and Cancer 2015 10:44
    Content type: Research Article Published on:

  29. Cytomegalovirus reactivation can be life threatening. However, little evidence on its incidence in solid cancers is available. Therefore our single center Cytomegalovirus polymerase chain reaction database wit...

    Authors: Konstantin Schlick, Michael Grundbichler, Jutta Auberger, Jan Marco Kern, Markus Hell, Florian Hohla, Georg Hopfinger and Richard Greil
    Citation: Infectious Agents and Cancer 2015 10:45
    Content type: Short Report Published on:

  30. The aberrant expression of miR-23b is involved in the development and progression of cancer. The aim of this study was to evaluate the potential role of methylation in the silencing of miR-23b in cervical canc...

    Authors: Gabriela Elizabeth Campos-Viguri, Hilda Jiménez-Wences, Oscar Peralta-Zaragoza, Gricenda Torres-Altamirano, Diana Guillermina Soto-Flores, Daniel Hernández-Sotelo, Luz Del Carmen Alarcón-Romero, Marco Antonio Jiménez-López, Berenice Illades-Aguiar and Gloria Fernández-Tilapa
    Citation: Infectious Agents and Cancer 2015 10:42
    Content type: Research Article Published on:

  31. We previously conducted a population-based screening trial of high-risk human papillomavirus (hrHPV) testing and conventional cytology, demonstrating higher sensitivity (92.7 % vs 22.1 % for CIN2+) but lower p...

    Authors: Marcela Lagos, Vanessa Van De Wyngard, Helena Poggi, Paz Cook, Paola Viviani, María Isabel Barriga, Martha Pruyas and Catterina Ferreccio
    Citation: Infectious Agents and Cancer 2015 10:43
    Content type: Research Article Published on:

  32. The main objective of our study was to evaluate the colposcopist ability to correctly identify the worst area of a cervical lesion where biopsy should be performed; the secondary objective was to investigate t...

    Authors: Giuseppe Bifulco, Nicoletta De Rosa, Giada Lavitola, Roberto Piccoli, Alessandra Bertrando, Valentina Natella, Costantino Di Carlo, Luigi Insabato and Carmine Nappi
    Citation: Infectious Agents and Cancer 2015 10:47
    Content type: Research Article Published on:

  33. Although the inclusion of the HPV vaccine has been registered in Spain since 2007, vaccination rates are lower than expected. The patients wish to be vaccinated is heavily influenced by information they have r...

    Authors: M. Reyes Oliver Pérez, Victoria Bravo Violeta, Ana Vazquez del Campo, Cristina Ruiz, Sonia Yáñez Castaño, Laura P. Pérez Conde and Jesús S. Jiménez López
    Citation: Infectious Agents and Cancer 2015 10:41
    Content type: Research Article Published on:

  34. Head and neck squamous cell cancers are among the most aggressive. Their incidence and mortality rates are relatively lower in Middle Africa than worldwide, but in Gabon, these rates tend to be 2–3 fold higher...

    Authors: Ingrid Labouba, Chloé Bertolus, Hervé I. Koumakpayi, Ernest Belembaogo, Jérôme Miloundja and Nicolas Berthet
    Citation: Infectious Agents and Cancer 2015 10:40
    Content type: Commentary Published on:

    The Erratum to this article has been published in Infectious Agents and Cancer 2016 11:8

  35. The association between HIV viremia and non-AIDS-defining cancers (NADCs) is not well characterized. Viremia may contribute directly or indirectly to cancer development and may have a differential impact on va...

    Authors: David J. Riedel, Anne F. Rositch and Robert R. Redfield
    Citation: Infectious Agents and Cancer 2015 10:38
    Content type: Short Report Published on:

  36. Epidemiological studies have examined the association between human papillomavirus (HPV) and breast cancer, but the findings are inconclusive. This study aimed to detect the prevalence of HPV in breast cancer ...

    Authors: Yi Zhou, Jinyuan Li, Yuting Ji, Ming Ren, Bo Pang, Ming Chu and Lanlan Wei
    Citation: Infectious Agents and Cancer 2015 10:36
    Content type: Research Article Published on:

  37. The role of Merkel cell polyomavirus (MCV) infection in the etiology of non-melanoma skin cancers, other than Merkel cell carcinoma, is unclear. Previously, we reported a significant association between seropo...

    Authors: Shalaka S. Hampras, Angelika Michel, Markus Schmitt, Tim Waterboer, Lena Kranz, Tarik Gheit, Kate Fisher, Vernon K. Sondak, Jane Messina, Neil Fenske, Basil Cherpelis, Massimo Tommasino, Michael Pawlita and Dana E. Rollison
    Citation: Infectious Agents and Cancer 2015 10:35
    Content type: Short Report Published on:

  38. The aim of this study was to analyze the prevalence of HPV and EBV in oral and oropharyngeal squamous cell carcinoma in south-eastern Poland. The correlation between viral infection, OSCC, alcohol use, tobacco...

    Authors: Dorota Polz-Gruszka, Kamal Morshed, Agnieszka Stec and Małgorzata Polz-Dacewicz
    Citation: Infectious Agents and Cancer 2015 10:37
    Content type: Research Article Published on:

  39. The neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), two low cost, routinely available inflammatory indices, have been found to be associated with risk of death in patients with sol...

    Authors: Elena Raffetti, Francesco Donato, Francesco Castelli, Franco Maggiolo, Giampiero Carosi and Eugenia Quiros-Roldan
    Citation: Infectious Agents and Cancer 2015 10:34
    Content type: Research Article Published on:

  40. Sub-Saharan countries including Nigeria have the highest burden of Human Papillomavirus (HPV) infection in the world. Most studies on HPV surveillance in Nigeria were done in the southern part of the country. ...

    Authors: Mohammed Mohammed Manga, Adeola Fowotade, Yusuf Mohammed Abdullahi, Aliyu Usman El-nafaty, Danladi Bojude Adamu, Hamidu Umar Pindiga, Rasheed Ajani Bakare and Abimbola Olu Osoba
    Citation: Infectious Agents and Cancer 2015 10:39
    Content type: Research Article Published on:

  41. Viral infections and the burden of high-grade intraepithelial neoplasias (HIN) and invasive carcinomas (IC) associated to infections by human papillomavirus (HPV) types may be prevented by type-specific anti-H...

    Authors: Claudia Magaña-León, Cuauhtémoc Oros and Rubén López-Revilla
    Citation: Infectious Agents and Cancer 2015 10:33
    Content type: Research Article Published on:

    The Erratum to this article has been published in Infectious Agents and Cancer 2016 11:11

  42. Prostate cancer causes the highest number of cancer-related deaths in Jamaican men. It is not known whether rural-dwelling men present with worse disease than urban-dwelling men at initial presentation. Since ...

    Authors: William D. Aiken, Kieron S. Jones, Camille Ragin and Kenneth James
    Citation: Infectious Agents and Cancer 2015 10:32
    Content type: Research Article Published on:

  43. Previous investigations on the association of human papillomavirus (HPV) and human bladder cancer have led to conflicting results. The aim of this study was to determine if low and high risk HPV play a role in...

    Authors: Sebastian C. Schmid, Leonore Thümer, Tibor Schuster, Thomas Horn, Florian Kurtz, Julia Slotta-Huspenina, Judith Seebach, Michael Straub, Tobias Maurer, Michael Autenrieth, Hubert Kübler, Margitta Retz, Ulrike Protzer, Jürgen E. Gschwend and Dieter Hoffmann
    Citation: Infectious Agents and Cancer 2015 10:31
    Content type: Research Article Published on:

  44. Cat-scratch disease (CSD) is a common infection in children; however, the wide spectrum of its clinical picture may lead to delayed diagnosis. An unusual presentation of CSD includes in the differential diagno...

    Authors: Katarzyna Mazur-Melewska, Katarzyna Jończyk-Potoczna, Anna Mania, Paweł Kemnitz, Jarosław Szydłowski, Wojciech Służewski and Magdalena Figlerowicz
    Citation: Infectious Agents and Cancer 2015 10:30
    Content type: Research Article Published on:

  45. Identification of different HPV subtypes in unidentified communities provides sufficient information for screening and monitoring potential impact of a vaccination program. Therefore, the aim of this study was...

    Authors: Hussain Gadelkarim Ahmed, Saleh Hussein Bensumaidea and Ibraheem M. Ashankyty
    Citation: Infectious Agents and Cancer 2015 10:29
    Content type: Research Article Published on:

  46. A few viruses have been detected in prostate cancer, however their role in the development of this malignancy has not been determined. The aim of this study was to analyze the presence and functionality of hum...

    Authors: Hector Rodríguez, Jorge Levican, Juan P. Muñoz, Diego Carrillo, Mónica L. Acevedo, Aldo Gaggero, Oscar León, Tarik Gheit, Omar Espinoza-Navarro, Jorge Castillo, Iván Gallegos, Massimo Tommasino and Francisco Aguayo
    Citation: Infectious Agents and Cancer 2015 10:27
    Content type: Research Article Published on:

  47. Sub-Sahara Africa hosts up to 71 % of all HIV infected people in the world. With this high incidence of Human immunodeficiency virus ( HIV) comes the burden of co-morbidities such as malignant and premalignant...

    Authors: Emily A. Rogena, Kenneth O. Simbiri, G. De Falco, L. Leoncini, Leona Ayers and J. Nyagol
    Citation: Infectious Agents and Cancer 2015 10:28
    Content type: Research Article Published on:

  48. The identification of suited early detection tests is one among the multiple requirements to reduce cervical cancer incidence in developing countries.

    Authors: Caroline Wangari Ngugi, Dietmar Schmidt, Karanja Wanyoro, Hamadi Boga, Peter Wanzala, Anne Muigai, John Mbithi, Magnus von Knebel Doeberitz and Miriam Reuschenbach
    Citation: Infectious Agents and Cancer 2015 10:25
    Content type: Research Article Published on:

  49. We aimed to clarify the possible role of human papillomavirus (HPV) infection in the malignant transformation of sinonasal inverted papilloma (IP).

    Authors: Yukashi Yamashita, Masahiro Hasegawa, Zeyi Deng, Hiroyuki Maeda, Shunsuke Kondo, Asanori Kyuna, Sen Matayoshi, Shinya Agena, Takayuki Uehara, Hideaki Kouzaki, Takeshi Shimizu, Taro Ikegami, Akira Ganaha and Mikio Suzuki
    Citation: Infectious Agents and Cancer 2015 10:23
    Content type: Research Article Published on:

  50. NRLP1 (rs12150220, rs9889625, rs9900356, rs6502867, rs2670660) and NLRP3 (rs35829419, rs10754558) polymorphisms have been analyzed in 69 subjects with documented asbestos exposure and dea...

    Authors: Violetta Borelli, Ronal R Moura, Elisa Trevisan and Sergio Crovella
    Citation: Infectious Agents and Cancer 2015 10:26
    Content type: Letter to the Editor Published on:

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