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Fig. 3 | Infectious Agents and Cancer

Fig. 3

From: Microendoscopy in vivo for the pathological diagnosis of cervical precancerous lesions and early cervical cancer

Fig. 3

Characteristics of HSIL and more severe lesions after methylene blue staining under microendoscopy. (a) The columnar epithelial cells of the cervical canal were distributed as feathery or papillary aggregates in HSIL patients. (b) The columnar cells in the cervical canal were disordered, and the structure of cervical glands was obscure in the AIS patient. (c) The columnar epithelial cells were replaced by neoplastic squamous epithelial cells and the normal structure of cervical glands disappeared in SCC patients. (d-f) Enlarged and irregular hyperchromatic nuclei were seen on the surface of inverse mosaic vessels (d), cotton-like punctate blood vessels (e), and spiral-shaped atypical vessels (f) in HSIL, AIS, and SCC patients separately. (g-h) There was a large number of lymphocytes around the lesions of HSIL (g) and SCC (h). (i) Possible lymph node structures around cancer cells were observed in SCC patients

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