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Table 2 The information of review articles

From: The correlation between Trichomonas vaginalis infection and reproductive system cancer: a systematic review and meta-analysis

Title

First author

Year

Conclusion

T. vaginalis causes cancer

Infection and cervical intraepithelial neoplasia

Boyle DC

1999

The risk of cervical neoplasia in the presence of T. vaginalis is about twice that in normal, which may be related to the production of nitrosamine

Yes

Trichomonas vaginalis: paradigm of a successful sexually transmitted organism

Rughooputh S

2005

T. vaginalis can be classified as one of the most important auxiliary factors in the pathogenesis of cervical cancer

Yes

Sexually transmitted infections and risk of prostate cancer: review of historical and emerging hypotheses

Sutcliffe S

2014

T. vaginalis promotes prostate cancer through an IgE mediated anti flagellar hormone inflammatory immune mechanism, while T. vaginalis may promote cancer by directly damaging or dissolving prostate epithelial cells

Yes

Association of Genital Infections Other Than Human Papillomavirus with Pre-Invasive and Invasive Cervical Neoplasia

Ghosh I

2016

T. vaginalis infection has a higher risk of cervical precancerous lesions and neoplastic lesions

Yes

The dawn of novel STI prevention methods: modelling potential unintended effects of changes in cervical cancer screening guidelines on trichomoniasis

Rönn MM

2018

Patients infected with hrHPV are more likely to be infected with T. vaginalis than those not infected with hrHPV

Yes