Assessing Epstein–Barr virus in gastric cancer: clinicopathological features and prognostic implications

Table 1 Relationship between EBV infection and clinicopathologic characteristics

Characteristics	EBV infection		p value
Characteristics	Positive	Negative	p value
Sex			0.001
Male	46	238
Female	7	129
Age (years)			0.421
≤ 60	31	193
> 60	22	174
Location			0.599
Proximal	14	109
Distal	39	255
Tumor size			0.799
≤ 5 cm	29	209
> 5 cm	21	140
Differentiation			0.146
Well	6	72
Poor	47	295
WHO classification			0.190
Well differentiated adenocarcinoma	6	72
Poorly differentiated adenocarcinoma	46	271
Mucinous adenocarcinoma	0	12
Signet ring cell carcinoma	1	12
Tumor invasion depth			0.045
T1–T2	18	79
T3–T4	35	288
Lymph node metastasis			0.099
N0	22	111
N+	31	256
Distant metastasis			0.124
M0	46	299
M1	5	68
TNM stage			0.001
I-II	30	121
III-IV	22	245
MSI status			0.275
MSS	10	41
MSI-H	0	5
HER2 status			0.928
Negative	9	64
Positive	3	20
AFP			0.322
Normal	39	262
High	2	6
CA19-9			0.247
Normal	36	215
High	5	53
CA125			1.000
Normal	26	242
High	4	37
CEA			0.039
Normal	47	221
High	2	39

ISSN: 1750-9378