Case | Discovery time(week) | classification | First symptoms | Medication | PD-1 interrupt | Recovery of thyroid function | Tumor evaluation | Prognosis |
---|---|---|---|---|---|---|---|---|
1 | 8 | Primary hyperthyroidism | Palpitation | Methimazole, propranolol | Yes | Full recovery | shrinkage | Persistence |
2 | 12 | Secondary hyperthyroidism | Loss of appetite, fatigue | Levothyroxine | Yes | Not recovered | progression | Death |
3 | 1 | Secondary hyperthyroidism | Loss of appetite, fatigue, edema | Levothyroxine | Yes | Not recovered | progression | Death |
4 | 26 | Primary hyperthyroidism | fatigue | Levothyroxine | No | Full recovery | progression | Persistence |
5 | 28 | Primary hyperthyroidism | Emaciation, fatigue | Methimazole | Yes | Partial recovery | Stability | Persistence |
6 | 36 | Primary hyperthyroidism | Loss of appetite, fatigue | Levothyroxine | Yes | Full recovery | Stability | Persistence |
7 | 24 | Primary hyperthyroidism | Edema | Levothyroxine | Yes | Full recovery | progression | Persistence |
8 | 12 | Primary hyperthyroidism | Edema, fatigue | Levothyroxine | Yes | Full recovery | Stability | Persistence |
9 | 3 | Primary hyperthyroidism | Fatigue, fidgety | unclear | Yes | Partial recovery | progression | Persistence |
10 | 35 | Secondary hyperthyroidism | Edema, fatigue | non-administration | Yes | unclear | progression | Persistence |