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Table 1 Summary of the included studies reporting prevalence of Blastocystis hominis in CRC patients

From: Are Blastocystis hominis and Cryptosporidium spp. playing a positive role in colorectal cancer risk? A systematic review and meta-analysis

References

Country

Study design

Diagnostic methods

Statistical significant difference

Total case

Positive case

Blastocystis subtypes in case group

Total control

Positive control

Blastocystis subtypes in control group

QA

Ali et al. [23]

Egypt

CC*

Microscopic (modified trichrome stain), culture, and PCR

No significant differences (p value = 0.101)

100

52

ST1 (1), ST2 (2), ST3 (4), and ST7 (3)

100

42

ST1 (4), ST2 (2), and ST3 (4)

10

Mahmoudvand et al. [24]

Iran

CC

Microscopic (modified trichrome stain) and PCR

Significant differences (p value < 0.001)

67

16

 

67

6

 

9

Hawash et al. [25]

Saudi Arabia

CC

Microscopic

Significant differences (p value < 0.05)

75

20

 

25

2

 

9

Sulzyc Bielicka et al. [4]

Poland

CC

Microscopic and PCR

Significant differences (p value = 0.00409)

107

13

ST1 (2), ST2 (1), and ST3 (9)

124

3

ST1 (1) and ST3 (1)

10

Al-Dabbagh and Al-Mukhtar [26]

Iraq

CC

Microscopic (formalin saline) and ELISA (B. hominis antigen)

No significant differences (p value = 0.6956)

40

15

 

80

33

 

9

Mohamed et al. [27]

Saudi Arabia

CC

Microscopic, culture, and PCR

Significant differences (p value < 0.05)

74

22

ST1 (12) and ST5 (10)

80

12

ST1 (2), ST2 (7), and ST5 (3)

10

Kumarasamy et al. [28]

Malaysia

CC

Microscopic (formal ether concentration), culture, and PCR

Significant differences (p value < 0.05)

204

43

ST1 (9), ST2 (1), ST3 (26), ST1 + 2 (2), ST2 + 3 (4), and ST5 (1)

221

22

ST1 (6), ST2 (2), ST3 (7), ST2 + 3 (4), and ST5 (3)

10

Asghari et al. [29]

Iran

CS*

Microscopic (modified trichrome stain), culture, and PCR

 

4

2

ST3 (2)

   

5

Majeed et al. [30]

Iraq

CS

Microscopic

 

116

51

    

7

Esteghamati et al. [31]

Iran

CS

Microscopic and PCR

 

39

11

    

6

Zhang et al. [32]

China

CS

Microscopic and PCR

 

49

4

    

6

Yersal et al. [33]

Turkey

CS

Microscopic, culture, and PCR

 

66

5

ST1 (3) and ST3 (2)

   

7

Chandramathi et al. [34]

Malaysia

CS

Microscopic and culture

 

15

7

    

5

  1. *CC: Case–control
  2. *CS: Cross-sectional
  3. QA: Quality assessment