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Table 1 Baseline characteristics of the second follow-up data of HCC patients treated with TACE

From: Arterial chemoembolization for patients with hepatocellular carcinoma and elevated lactate dehydrogenase is associated with low survival: a cohort study

Characteristics

ΔLDH (U/L)

P# value

P$ value

> − 80, < 80

≤  − 80

 ≥ 80

N

444

217

88

0.997

0.639

Age (years, median ± SD)

52.1 ± 12.2

53.0 ± 12.4

51.3 ± 11.4

  

 < 55

225 (50.7%)

110 (50.7%)

47 (53.4%)

  

 ≥ 55

219 (49.3%)

107 (49.3%)

41 (46.6%)

  

Gender

   

0.292

0.436

 Male

408 (91.9%)

194 (89.4%)

83 (94.3%)

  

 Female

36 (8.1%)

23 (10.6%)

5 (5.7%)

  

PS score

   

0.001

0.001

 0

384 (86.5%)

117 (54%)

64 (72.7%)

  

 1

60 (13.5%)

40 (18.4%)

24 (17.3%)

  

Diameter of main tumour (cm)

   

0.035

< 0.001

 < 5

200 (45.0%)

79 (36.4%)

16 (18.2%)

  

 ≥ 5

244 (55.0%)

138 (63.6%)

72 (81.8%)

  

AFP (ng/mL)

   

0.205

0.001

 < 25

209 (47.1%)

93 (42.9%)

23 (26.1%)

  

 ≥ 25

214 (48.2%)

118 (54.4%)

58 (65.9%)

  

Hgb (g/L)

   

0.567

0.129

 < 120

108 (24.3%)

49 (22.6%)

28 (31.8%)

  

 ≥ 120

297 (66.9%)

151 (69.6%)

52 (59.1%)

  

WBC (109/L)

   

0.072

< 0.001

 < 11

380 (85.6%)

184 (84.8%)

65 (73.9%)

  

 ≥ 11

22 (5.0%)

19 (8.8%)

15 (17.0%)

  

No. of intrahepatic lesions

   

0.021

< 0.001

 0

198 (44.6%)

79 (36.4%)

16 (18.2%)

  

 ≤ 3

106 (23.9%)

46 (21.2%)

17 (19.3%)

  

 > 3

140 (31.5%)

92 (42.4%)

55 (62.5%)

  

Location of lesions

   

0.048

< 0.001

 None

198 (4.3%)

79 (36.4%)

16 (18.2%)

  

 Left/right

109 (24.5%)

51 (23.5%)

26 (29.5%)

  

 Both

137 (30.9%)

87 (40.1%)

46 (52.3%)

  

Child–Pugh class

     

 A

344 (77.5%)

178 (82.0%)

48 (54.5%)

0.178

< 0.001

 B

100 (22.5%)

39 (18.0%)

40 (45.5%)

  
  1. ΔLDH = the difference between the LDH value at the second follow-up and the baseline LDH value. The chi-square test for categorical measurement and the Kruskal–Wallis test for continuous measurement were used to compare the differences. Resolve missing data with multiple complementation method. #ΔLDH ≤ − 80 vsΔLDH within ± 80. $ΔLDH ≥ 80 vs ΔLDH within ± 80