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Table 5 Comparison of the genotype specific Ct values in each histology grades among different age group

From: Verification of the association of the cycle threshold (Ct) values from HPV testing on Cobas4800 with the histologic grades of cervical lesions using data from two population-based cervical cancer screening trials

Histology grade

HrHPV

HPV16

Pooled 12-HPV

No. of participants

CtV (mean ± SD)

No. of participants

CtV (mean ± SD)

No. of participants

CtV (mean ± SD)

 ≤ CIN1

30–39

344

31.6 (± 5.5)

76

33.3 (± 4.7)

237

31.1 (± 5.7)

40–49

513

31.3 (± 5.3)

74

31.4 (± 4.8)

409

31.2 (± 5.4)

50–59

339

31.8 (± 4.9)

43

31.7 (± 4.7)

260

31.7 (± 5.1)

CIN2+

30–39

60

28.4 (± 5.4)a

38

27.4 (± 4.3)a

21

29.8 (± 6.7)

40–49

82

28 (± 4.3)a

36

26.7 (± 2.8)a

42

28.6 (± 4.8)a

50–59

38

28.4 (± 4.8)a

15

27 (± 2.4)a

21

28.7 (± 5.5)

  1. aCompared with ≤ CIN1, P < 0.05
  2.  ≤ CIN1 includes Non-CIN and CIN1; CIN2+ includes CIN2, CIN3 and cancer