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Table 5 Concordance between ChapterDx HPV-STI NGS assay and Roche cobas assay for 14 high-risk HPVs

From: A comprehensive HPV-STI NGS assay for detection of 29 HPV types and 14 non-HPV sexually transmitted infections

 

Roche cobas 4800

Negative

Positive

Total

Agreement

kappa

ChapterDx HPV-STI NGS Assay

 HPV16

     

  Negative

183

1

184

98.5

0.967 (95% CI 0.934–0.999)

  Positive

3

87

90

  

  Total

186

88

274

  

 HPV18

     

  Negative

250

3

253

98.5

0.901 (95% CI 0.805–0.997)

  Positive

1

20

21

  

  Total

251

23

274

  

 Othersb (12 HR Types)

     

  Negative

79

7

86

96.0

0.906 (95% CI 0.851–0.960)

  Positive

4

184

188

  

  Total

83

191

274

  
  1. aInterpretation values: poor (< 0.20), fair (0.21–0.40), moderate (0.41–0.60), good (0.61–0.80), very good (0.81–1.00)
  2. bHPV 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68
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Infectious Agents and Cancer

ISSN: 1750-9378

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