Table 4 Association between HPV-16 and -18 L1 and (E6 and E7) seropositivity and cervical cancer
Serology markers | Cases (N = 1,346) | Controls (N = 2,532) | Adjusted OR (95% CI) |
|---|---|---|---|
n (%) Seropositive | n (%) Seropositive | ||
HPV16 L1 | 332 (24.4) | 373 (14.7) | 1.74 (1.45–2.07) |
HPV18 L1 | 292 (21.7) | 409(16.2) | 1.31 (1.10–1.56) |
HPV type 16 | |||
HPV16 E6 | 467 (35.9) | 70 (2.8) | 21.96 (16.61–29.02) |
HPV16 E7 | 309 (24.7) | 97 (3.8) | 7.93 (6.16–10.22) |
HPV16 E6 & E7 | 209 (23.3) | 11 (0.5) | 69.20 (37.07–129.18) |
HPV type 18 | |||
HPV18 E6 | 120 (8.9) | 54 (2.1) | 4.67 (3.30–6.59) |
HPV18 E7 | 235 (18.6) | 68 (2.7) | 8.94 (6.64–12.03) |
HPV18 E6 &E7 | 64 (5.9) | 5 (0.2) | 38.61 (15.13–98.53) |
HPV types 16 or 18 | |||
HPV16/18 E6/E7 | 746 (56.8) | 255 (10.1) | 13.63 (11.32–16.41) |