Fig. 5From: The degradation of Rap1GAP via E6AP-mediated ubiquitin-proteasome pathway is associated with HPV16/18-infection in cervical cancer cellsKnocking down E6AP activates the autophagy degradation pathway of Rap1GAP in HPV-positive cervical cancer cells. Cells, as indicated, were transfected with siRNA for E6AP to silence the expression of E6AP. The knocking-down efficiency was evaluated by detecting the levels of E6AP in the cells. Then, the autophagy markers p62 and LC3 II/LC3 I were checked to assess the levels of autophagyBack to article page