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Fig. 4 | Infectious Agents and Cancer

Fig. 4

From: The degradation of Rap1GAP via E6AP-mediated ubiquitin-proteasome pathway is associated with HPV16/18-infection in cervical cancer cells

Fig. 4

Knocking down E6AP increase the levels of Rap1GAP in HPV-positive cervical cancer cells. HeLa, SiHa and C33A cells were transfected with siRNA for E6AP, and the levels of E6AP were detected by western blotting to check the efficiency of knocking down. Then, the levels of Rap1GAP and p53 were detected by western blotting after silencing E6AP. *pā€‰<ā€‰0.05

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