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Table 1 Clinical characteristic of patients with breast cancer involved in the study

From: Low frequency of HPV positivity in breast tumors among patients from south-central Poland

Characyeristics

Numeber of cases

%

All (%)

383

100.0

Age

  

< 50 years

124

32.4

≥ 50 years

259

67.6

Tumour size

  

T1

108

28.2

T2

268

70.0

T3

7

1.8

Nodal status

  

N0

53

13.8

N1

238

62.2

N2

79

20.6

N3

13

3.4

Grade

  

G1

37

9.7

G2

145

37.8

G3

201

52.5

Oestrogen receptor status

  

Positive

280

73.1

Negative

103

26.9

Progesterone receptor status

  

Positive

263

68.7

Negative

120

31.3

HER2 status

  

Overexpressing

187

48.8

Not overexpressing

196

51.2

Ki-67LIa

  

≤ 19.7%

101

26.4

> 19.7%

282

73.6

Breast cancer immunophenotypesb

  

LA

56

14.6

LB HER2

92

24.1

LB HER2+

125

32.6

HER2+

59

15.4

TN

51

13.3

HPV infection—nested PCR

  

Yes

17

4.4

No

366

95.6

HPV infection—qPCR

  

Yes

2

0.5

No

381

99.5

P16 immunoespression

  

Yes

2

0.5

No

381

99.5

  1. Ki-67LI Ki-67 labelling index, LA luminal A, LB luminal B, TN triple negative
  2. aCut-off point from minimal P value method
  3. bImmunophenotypes indicated on the basis of ER, PgR, HER2 and Ki-67 expression according to St. Gallen International Expert Consensus on The Primary Therapy of Early Breast Cancer 2013[26]