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Fig. 3 | Infectious Agents and Cancer

Fig. 3

From: Metagenomic analysis to identify novel infectious agents in systemic anaplastic large cell lymphoma

Fig. 3

Application of virID pipeline to identify viral sequences associated with ALCL. This figure highlights the findings of applying virID algorithm to classify unmapped reads following GATK-PathSeq using the virID assembly-based approach. A and B represent the taxonomical classification of reads into viral genera after subjecting the contigs to nucleotide (MegaBLAST) and translated amino acid (DIAMOND) searches against their respective reference databases. The units used are log10 reads per million human reads. Samples are grouped on the x-axis as ALK-positive ALCL, ALK-negative ALCL, HIV-positive ALCL, EBER-negative DLBCL, EBER-positive DLBCL, and breast cancer. Viral genera identified are listed on the y-axis. ALCL, anaplastic large cell lymphoma; ALK, anaplastic lymphoma kinase; DLBCL, diffuse large B-cell lymphoma; HIV, human immunodeficiency virus

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