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Table 5 Univariate analyses in HBsAg-positive and -negative DLBCL patients

From: Clinicopathological and prognostic features of hepatitis B virus-associated diffuse large B-cell lymphoma: a single-center retrospective study in China

Characteristics HBsAg-positive DLBCL patients HBsAg- negative DLBCL patients
N (total = 127) Log-rank P-value N (total = 293) Log-rank P value
Sex     
 Male 79 0.5748 158 0.6699
 Female 48   135  
Age     
 > 60 22 0.0377 97 < 0.0001
 ≤ 60 105   196  
Ann Arbor stage     
 I 18 0.0002 48 < 0.0001
 II 37   113  
 III 34   44  
 IV 38   88  
B symptoms     
 Present 28 0.0003 76 0.697
 Absent 99   217  
Elevated LDH     
 Present 67 0.0487 135 < 0.0001
 Absent 56   158  
 Unknown 4   
Treatment with rituximab     
 Yes 60 0.0152 143 0.002
 No 67   150  
Spleen involvement     
 Yes 28 0.034 19 0.002
 No 99   274  
Bcl-2&Myc positive     
 Yes 34 0.048 57 0.037
 No 22   59  
 Unknown 71   177  
Cell of origin     
 GCB 47 0.124 107 0.103
 Non-GCB 80   186  
HBV DNA copies     
 < 1000 copies/ml 51 0.536
 > 1000 copies/ml 69    
 Unknown 7    
HBeAg     
 Positive 25 0.534
 Negative 95    
 Unknown 7