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Table 3 Antibody titers’ fold changes (FC) in previously infected and not previously infected cohorts of healthcare providers to monitor vaccine immune responses

From: Vaccination strategy and anti - SARS-CoV-2 S titers in healthcare workers of the INT – IRCCS “Fondazione Pascale” Cancer Center (Naples, Italy)

Analyzed cohorts

Mean FC

Min FC

Max FC

n (%)

PreViously infected subjects

 Post I / Pre

1.8

0.0

3.8

35 (100.0%)

NotPreviously infected subjects

 Post I / Pre

1.6

0.0

3.6

158 (100.0%)

 Post II / Post I

1.9

0.2

3.8

158 (100.0%)

 Post II / Pre

3.5

1.4

3.8

158 (100.0%)

 Post II/Pre \( \overline{x} \) ≤ 3.1

2.6

1.4

3.1

30 (19.0%)

 Post II/Pre 3.1< \( \overline{x} \) ≤ 3.3

3.2

3.1

3.3

12 (7.6%)

 Post II/Pre 3.3< \( \overline{x} \) ≤ 3.8

3.7

3.3

3.8

116 (73.4%)

 Post II/Pre = 3.8

3.8

  

72 (45.6%)

  1. Previously infected subjects = subjects infected to SARS-CoV-2
  2. Not previously infected subjects = subjects not infected to SARS-CoV-2
  3. Pre = anti - SARS-CoV-2 S titers before the first dose
  4. Post I = anti - SARS-CoV-2 S titers 20 days after the first dose
  5. Post II = anti - SARS-CoV-2 S titers 8 days after the second dose
  6. mean FC = mean fold changes of anti - SARS-CoV-2 S mean geometric titers
  7. n (%) = number of subjects (percentage)