Emerging role of human polyomaviruses 6 and 7 in human cancers

Table 4 Prevalence of HPyV6 and HPyV7 in non-cutaneous other human malignancies

Tumor	Specimen	Samples n	Method	HPyV6 Positive n (%)	HPyV7 Positive n (%)	Reference
BC	FF	54	rt-PCR	1 (2)	1 (2)	[75]
LSCC	FF	7	Luminex platform (Multiplex PCR)	1 (14.3)	ND	[76]
TETs	FFPE	37	FISH/PCR/Seq/IHC	ND	23 (62.2)	[31]
TSCC	FF	38	qPCR	2 (5.3)	1 (2.6)	[57]
TC	FF and FFPE	112	qPCR	6 (5.4)	2 (1.8)	[58]
CCA	FFPE	42	PCR/FISH/RISH/IHC	4 (9.5)	19 (45.2)	[77]

BC breast cancer, CCA cholangiocarcinoma, FFPE formalin-fixed paraffin-embedded, FF Freshly frozen tissue, FISH fluorescence in situ hybridization, LSCC laryngeal squamous cell carcinoma, ND not detected, PCR polymerase chain reaction, qPCR quantitative polymerase chain reaction, rt-PCR real-time polymerase chain reaction, RISH RNA fluorescence in situ hybridization, Seq Sanger sequencing, TC tonsillar carcinoma, TETs thymic epithelial tumors, TSCC tonsillar squamous cell carcinoma

ISSN: 1750-9378