Skip to main content

Table 3 Prevalence of HPyV6 and HPyV7 in primary cutaneous malignancies

From: Emerging role of human polyomaviruses 6 and 7 in human cancers

Cancer Specimen types Samples n Method HPyV6 Positive n (%) HPyV7 Positive n (%) Reference
MM FFPE 47 rt-PCR/Seq. 2 (4.3) 2 (4.3) [25]
AK FFPE 31 qPCR 1 (3) ND [27]
AK FFPE 92 Seq. 4 (4.3) NA [69]
AK FFPE 2 qPCR ND 1 (50) [53]
VK FFPE 4 qPCR 3 (75) 3 (75) [53]
BCC FFPE 18 qPCR 10 (5.5) ND [29]
BCC FFPE 41 qPCR 3 (7) ND [27]
BCC FFPE 50 rt-PCR/Seq. 1 (2) 2 (4) [25]
BCC FFPE 109 PCR/Seq./FISH 23 (21.1) NA [68]
SCC FFPE 8 qPCR 1 (12) ND [27]
SCC FFPE 21 qPCR 8 (38) ND [29]
SCC FFPE 52 qPCR 2 (4) ND [27]
SCC FFPE 86 PCR/Seq./FISH 8 (9.3) NA [68]
SCC FFPE 63 rt-PCR/Seq. 2 (3.2) 1 (1.6) [25]
SCC IN CLL cases who had BMT FFPE 3 Bead-based
multiplex PCR
1 (33.3) ND [28]
SCC FFPE 11 qPCR 4 (36.4) 6 (54.5) [53]
SCC FFPE 17 (6 patients) rt-PCR/IHC 17 (100) 17 (100) [26]
KA FFPE 42 qPCR 2 (5) ND [27]
KA FFPE 59 PCR/Seq/FISH 25 (42.3) NA [68]
TB FFPE 45 PCR/Seq 10 (22.2) NA [68]
MCC FFPE 20 qPCR 2 (10) ND [29]
MCC FFPE 28 rt-PCR 1 (3.5) 1 (3.5) [30]
CTCLs FFPE 116 rt-PCR 6 (5.20) 1 (0.90) [70]
CTCLs FF 71 rt-PCR 13 (18.3) ND [24]
CTCLs FF and FFPE 35 rt-PCR 7 (20) 3 (8.6) [71]
Total   1072   157/1072 (14.6) 37/681 (5.4)  
  1. AK actinic keratosis, BCC basal cell carcinoma, BMT bone marrow transplantation, CLL chronic lymphocytic leukemia, CTCLs cutaneous T-cell lymphomas, FFPE formalin-fixed paraffin-embedded, FISH fluorescence in situ hybridization, IHC immunohistochemistry, FF fresh frozen tissue, KA keratoacanthoma, MCC Merkel cell carcinoma, MM malignant melanoma, NA not applicable, ND not detected, PCR polymerase chain reaction, qPCR quantitative polymerase chain reaction, rt-PCR real-time polymerase chain reaction, SCC squamous cell carcinoma, Seq Sanger sequencing, TB trichoblastoma, VK verrucous keratosis