Skip to main content

Table 1 Seroprevalence of HPyV6 and HPyV7 antibodies in serum using ELISA or Luminex platform

From: Emerging role of human polyomaviruses 6 and 7 in human cancers

Source of the specimen Age (y) Samples n HPyV6 Positive n (%) HPyV7 Positive n (%) Assay Reference
VLP GST VLP GST
18–65 (y) Blood donors.
< 18 or > 65 (y)
From discarded lab samples
1–4 48 18 (37.5)   5 (10.4)   ELISA [39]
5–9 69 40 (57.9)   23 (33.3)  
10–14 92 65 (70.6)   41 (44.6)  
15–19 89 55 (61.8)   32 (36)  
20–29 49 43 (87.8)   22 (44.9)  
30–39 73 49 (67.1)   31 (42.5)  
40–49 105 89 (84.8)   62 (59.1)  
50–59 95 78 (82.1)   64 (67.4)  
60–69 100 88 (88)   68 (68)  
70–79 52 46 (88.5)   42 (80.8)  
≥ 80 56 55 (98.2)   48 (85.7)  
Blood donors 20–29 96 82 (85.4) 77 (80.2) 58 (60.4) 68 (70.8) ELISA [37]
30–39 129 114 (88.4) 111 (86) 92 (71.3) 106 (82.2)
40–49 52 48 (92.3) 48 (92.3) 32 (61.5) 40 (76.9)
50–59 24 22 (91.7) 21 (87.5) 16 (66.7) 19 (79.2)
> 59 5 4 (80) 4 (80) 3 (60) 4 (80)
Serum obtained for routine lab tests 0–0.5 31   25 (80.6)   18 (58.1) Luminex platform [40]
0.6–1.9 63   14 (22.2)   12 (19)
2–3 62   21 (33.9)   12 (19.4)
4–5 58   26 (44.8)   19 (32.8)
6–7 58   29 (50)   21 (36.2)
8–9 70   44 (62.9)   27 (38.6)
10–14 55   31 (56.4)   21 (38.2)
15–19 59   38 (64.4)   25 (42.4)
20–29 59   39 (66.1)   30 (50.8)
30–39 64   41 (64.1)   35 (54.7)
40–49 54   34 (63)   33 (61.1)
50–59 58   46 (79.3)   36 (62.1)
60–69 54   50 (92.6)   45 (83.3)
> 70 54   50 (92.6)   46 (85.2)
Blood donors 18–29 208   156 (75.7)   117 (56.8) Luminex platform [38]
30–39 209   175 (84.5)   154 (74.4)
40–49 208   173 (83.6)   155 (74.9)
50–59 215   184 (85.6)   154 (71.6)
60–69 210   187 (89.5)   169 (80.9)
Blood donors   95 66 (69)   33 (35)   ELISA [23]
SCCs transplanted cases   110   65 (59)   57 (51.8) ELISA and Luminex platform [42]
Non-SCCs transplanted cases   207   137 (66.2)   85 (41)
Lung cancer   511 393 (76.9)   333 (65.2)   Luminex platform [43]
Controls   508 400 (78.7)   334 (65.8)  
  1. ELISA enzyme-linked immunosorbent assays, GST glutathione-S-transferase, SCC squamous cell carcinoma, VLP virus-like particles, (y) years old