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Fig. 2 | Infectious Agents and Cancer

Fig. 2

From: Genetic instability and anti-HPV immune response as drivers of infertility associated with HPV infection

Fig. 2

Stages of the fertilization and embryonal development compromised by HPV infection. Cells, tissues and embryo infected with HPVs at different stages of development are colored in grey tones. Black cross designates preterm termination of the embryonal development. Spontaneous clearance of HPVs from the epithelial tissues is well documented; no data exists on possibility of HPV clearance from the infected embryonal cells and/or fetus, this possibility is not excluded and is designated on the scheme with a question mark. Elements of the figure are adapted from [1, 2], Human placental project at https://www.nichd.nih.gov/research/supported/HPP/form and image of five month human fetus corresponding to the successful passage of 20 weeks of pregnancy (no spontaneous/preterm abortion), from https://www.pinterest.com/pin/441352832202220770/

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