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Table 8 The Value of Single and Combined Detection of Serum AFP, AFP-L3, CTCs in Predicting the Poor Short-term Efficacy after Microwave Ablation in HCC Patients

From: Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Index AUC P Sensitivity Specificity Youden index
AFP 0.532 <0.001 0.667(24) 0.594(41) 0.261
AFP-L3 0.586 <0.001 0.722(26) 0.652(45) 0.374
CTCs 0.659 <0.001 0.778(28) 0.681(47) 0.459
AFP+AFP-L3 0.746 <0.001 0.861(31) 0.696(48) 0.557
AFP+CTCs 0.781 <0.001 0.889(32) 0.710(49) 0.599
AFP-L3+CTCs 0.837 <0.001 0.917(33) 0.725(50) 0.642
AFP+AFP-L3+CTCs 0.896 <0.001 0.944(34) 0.768(53) 0.712