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Table 8 The Value of Single and Combined Detection of Serum AFP, AFP-L3, CTCs in Predicting the Poor Short-term Efficacy after Microwave Ablation in HCC Patients

From: Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Index

AUC

P

Sensitivity

Specificity

Youden index

AFP

0.532

<0.001

0.667(24)

0.594(41)

0.261

AFP-L3

0.586

<0.001

0.722(26)

0.652(45)

0.374

CTCs

0.659

<0.001

0.778(28)

0.681(47)

0.459

AFP+AFP-L3

0.746

<0.001

0.861(31)

0.696(48)

0.557

AFP+CTCs

0.781

<0.001

0.889(32)

0.710(49)

0.599

AFP-L3+CTCs

0.837

<0.001

0.917(33)

0.725(50)

0.642

AFP+AFP-L3+CTCs

0.896

<0.001

0.944(34)

0.768(53)

0.712