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Table 6 The Value of Single and Combined Detection of Serum AFP, AFP-L3, CTCs in Predicting the Recurrence of HCC Patients after Microwave Ablation

From: Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Index AUC P Sensitivity Specificity Youden index
AFP 0.552 <0.001 0.667(32) 0.614(35) 0.281
AFP-L3 0.619 <0.001 0.729(35) 0.684(39) 0.413
CTCs 0.651 <0.001 0.750(36) 0.702(40) 0.452
AFP+AFP-L3 0.703 <0.001 0.792(38) 0.737(42) 0.529
AFP+CTCs 0.767 <0.001 0.833(40) 0.754(43) 0.587
AFP-L3+CTCs 0.841 <0.001 0.854(41) 0.789(45) 0.643
AFP+AFP-L3+CTCs 0.917 <0.001 0.896(43) 0.825(47) 0.721