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Table 4 Analysis of the Value of Single and Combined Detection of Serum AFP, AFP-L3, CTCs in the Early Diagnosis of HCC

From: Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Index

AUC

P

Sensitivity

Specificity

Youden index

AFP

0.638

<0.001

0.643(92)

0.794(81)

0.437

AFP-L3

0.674

<0.001

0.734(105)

0.775(79)

0.509

CTCs

0.705

<0.001

0.818(117)

0.725(74)

0.543

AFP+AFP-L3

0.767

<0.001

0.881(126)

0.706(72)

0.587

AFP+CTCs

0.793

<0.001

0.909(130)

0.667(68)

0.576

AFP-L3+CTCs

0.817

<0.001

0.930(133)

0.686(70)

0.616

AFP+AFP-L3+CTCs

0.832

<0.001

0.972(139)

0.657(67)

0.629

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Infectious Agents and Cancer

ISSN: 1750-9378

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