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Table 4 Analysis of the Value of Single and Combined Detection of Serum AFP, AFP-L3, CTCs in the Early Diagnosis of HCC

From: Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Index AUC P Sensitivity Specificity Youden index
AFP 0.638 <0.001 0.643(92) 0.794(81) 0.437
AFP-L3 0.674 <0.001 0.734(105) 0.775(79) 0.509
CTCs 0.705 <0.001 0.818(117) 0.725(74) 0.543
AFP+AFP-L3 0.767 <0.001 0.881(126) 0.706(72) 0.587
AFP+CTCs 0.793 <0.001 0.909(130) 0.667(68) 0.576
AFP-L3+CTCs 0.817 <0.001 0.930(133) 0.686(70) 0.616
AFP+AFP-L3+CTCs 0.832 <0.001 0.972(139) 0.657(67) 0.629