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Table 10 The Value of Single and Combined Detection of Serum AFP, AFP-L3, CTCs in Predicting the Level of OS < 3 years for HCC Patients after Microwave Ablation

From: Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Index AUC P Sensitivity Specificity Youden index
AFP 0.546 <0.001 0.673(35) 0.625(25) 0.298
AFP-L3 0.595 <0.001 0.712(37) 0.675(27) 0.387
CTCs 0.647 <0.001 0.750(39) 0.700(28) 0.450
AFP+AFP-L3 0.749 <0.001 0.808(42) 0.750(30) 0.558
AFP+CTCs 0.820 <0.001 0.846(44) 0.775(31) 0.621
AFP-L3+CTCs 0.857 <0.001 0.865(45) 0.800(32) 0.665
AFP+AFP-L3+CTCs 0.923 <0.001 0.904(47) 0.825(33) 0.729