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Table 10 The Value of Single and Combined Detection of Serum AFP, AFP-L3, CTCs in Predicting the Level of OS < 3 years for HCC Patients after Microwave Ablation

From: Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Index

AUC

P

Sensitivity

Specificity

Youden index

AFP

0.546

<0.001

0.673(35)

0.625(25)

0.298

AFP-L3

0.595

<0.001

0.712(37)

0.675(27)

0.387

CTCs

0.647

<0.001

0.750(39)

0.700(28)

0.450

AFP+AFP-L3

0.749

<0.001

0.808(42)

0.750(30)

0.558

AFP+CTCs

0.820

<0.001

0.846(44)

0.775(31)

0.621

AFP-L3+CTCs

0.857

<0.001

0.865(45)

0.800(32)

0.665

AFP+AFP-L3+CTCs

0.923

<0.001

0.904(47)

0.825(33)

0.729