Fig. 7
From: Identification of key genes in hepatitis B associated hepatocellular carcinoma based on WGCNA
Functional Prediction of the Key Genes Involved in HBV Associated HCC. a Protein-Protein-Interaction (PPI) Network of the Key Genes Involved in HBV Associated HCC. GeneMANIA was applied to predict the function of key genes and construct the PPI network. The red rounds indicated key genes (query genes), and the khaki rounds indicated result genes. The different color lines between the rounds indicated distinct relationships between corresponding genes/proteins, such as co-expression, co-localization, physical interactions, predicted relations, shared protein domains, genetic interactions and pathway. b Visualization of the CELL CYCLE (hsa04110) KEGG pathway. The genes in the PPI network are highlighted in red. The different relations between proteins in the pathway are indicated in distinct types of lines. c The VIRAL CARCINOGENESIS pathways (hsa05203) related to the genes in PPI network. The genes in the PPI network are also highlighted in red