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Table 3 Factors associated with persistence (vs. clearance) of any hrHPV (n = 235 hrHPV+ at the screening visit)

From: Type-specific persistence, clearance and incidence of high-risk HPV among screen-positive Rwandan women living with HIV

 

N (%)

OR

95%CI

aOR

95%CI

CD4 (per mm3) (Screening Visit)

  ≥ 500 (ref)

111 (47.2)

1

–

1

–

 350–499

49 (20.9

1.43

0.73–2.81

1.46

0.67–3.15

 200–349

39 (16.6)

1.64

0.78–3.42

1.56

0.69–3.51

  < 200

23 (9.8)

2.37

0.93–6.05

2.48

0.84–7.35

 Missing

13 (5.5)

1.08

0.34–3.44

2.19

0.57–8.41

ptrenda=

 

0.04

0.06

Detectable HIV Viral Load (Screening Visit)

 No (ref)

183 (77.9)

1

–

1

–

 Yes

27 (11.5)

1.99

0.84–4.63

1.75

0.67–4.57

 Missing

25 (10.6)

0.47

0.19–1.13

0.34

0.12–0.98

Age Group (years) (Screening Visit)

 30–33 (ref)

54 (23.0)

1

–

1

–

 34–36

53 (22.6)

1.5

0.70–3.23

1.74

0.74–4.08

 37–42

63 (26.8)

1.1

0.52–2.25

0.80

0.34–1.83

 43–54

65 (27.7)

2.0

0.97–4.21

2.26

1.01–5.05

ptrend=

 

0.13

0.17

Follow-Up Time (Days)

 197–490 (ref)

66 (28.1)

1

–

1

–

 490–649

62 (26.4)

0.38

0.29–0.79

0.35

0.16–0.77

 650–820

49 (20.9)

0.89

0.43–1.86

0.94

0.41–2.14

 821–1161

52 (22.1)

0.68

0.32–1.41

0.74

0.33–1.67

 Missing

6 (2.6)

0.34

0.06–1.97

0.61

0.08–4.59

ptrenda=

 

0.68

0.93

Colposcopic Impression

 low-grade (ref)

207 (88.1)

1

–

1

–

 high-grade

21 (8.9)

23.1

3.0–175.52

24.90

3.08–201.22

 Missing

7 (3.0)

0.86

0.66–1.14

0.33

0.05–2.11

Number of hrHPV Types Detected at the Screening Visit

 1 (ref)

133 (56.6)

1

–

  

  ≥ 2

102 (43.4)

0.99

0.59–1.66

  
  1. amissing values excluded from tests of trend, OR unadjusted odds ratio, aOR adjusted odds ratio and 95%CI 95% confidence interval