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Table 1 General participant characteristics and results by persistence vs. clearance of hrHPV by AmpFire

From: Type-specific persistence, clearance and incidence of high-risk HPV among screen-positive Rwandan women living with HIV

Characteristic All Women Clearance Persistence p*
n = 298 n = 117 n = 118
n (%col) n (%col) n (%col)
Age Group (Years)
 30–33 70 (23.5) 31 (26.5) 23 (19.5) 0.19
 34–36 60 (20.1) 25 (21.4) 28 (23.7)
 37–42 82 (27.5) 35 (29.9) 28 (23.7)
 43–54 85 (28.5) 26 (22.2) 39 (33.0)
 Missing 1 (0.3) 0 (0.0) 0 (0.0)
Age at Sexual Initiation (Years)
  < 18 180 (60.4) 51 (43.6) 42 (35.6) 0.21
  ≥ 18 118 (39.6) 66 (56.4) 76 (64.4)
Number of Sexual Partners (Lifetime)
  ≤ 5 245 (82.2) 94 (80.3) 98 (83.1) 0.59
  ≥ 6 53 (17.8) 23 (19.7) 20 (16.9)
Number of Sexual Partners (Last 6 Months)
  ≤ 5 285 (95.6) 111 (94.8) 113 (95.8) 0.90
  ≥ 6 8 (2.7) 3 (2.6) 3 (2.5)
 Missing 5 (1.7) 3 (2.6) 2 (1.7)
Number of Children
  < 5 230 (77.2) 90 (76.9) 92 (78.0) 0.85
  ≥ 5 68 (22.8) 27 (23.1) 26 (22.0)
CD4 (per mm3) (Screening Visit)
  ≥ 500 (ref) 146 (49.0) 62 (53.0) 49 (41.5) 0.34
 350–499 64 (21.5) 23 (19.7 26 (22.0)
 200–349 48 (16.1) 17 (14.5) 22 (18.6)
  < 200 25 (8.4) 8 (6.8) 15 (12.7)
 Missing 15 (5.0) 7 (6.0) 6 (5.1)
On Anti-Retrovirals
 No 3 (1.0) 1 (0.9) 2 (1.7) 1.00
 Yes 293 (98.3) 115 (99.3) 115 (97.5)
 Missing 2 (0.7) 1 (0.9) 1 (0.9)
HIV Viral Loada (Screening Visit)
 Undetectable 236 (79.2) 91 (77.8) 92 (80.0) 0.04
 Detectable 28 (9.4) 9 (7.7) 18 (15.3)
 Missing 34 (11.4) 17 (14.5) 8 (6.8)
Time between Screening and Colposcopy Visits (Days)
 197–489 72 (24.2) 27 (23.1) 40 (33.9) 0.06
 490–649 73 (24.5) 39 (33.3) 22 (18.6)
 650–820 74 (24.8) 22 (18.8) 29 (24.6)
 821–1161 73 (24.5) 25 (21.4) 25 (21.9)
 Missing 6 (2.0) 4 (3.4) 2 (1.7)
VIA Result (Screening Visit)
 Negative 228 (76.5) 100 (85.5) 104 (88.1) 0.50
 Positive 68 (22.8) 15 (12.8) 14 (11.9)
 Missing 2 (0.7) 2 (1.7) 0 (0.0)
Number of hrHPV Types (Screening Visit)
 0 63 (21.1) 1.00
 1 133 (44.6) 66 (56.4) 67 (56.8)
  ≥ 2 102 (34.2) 51 (43.6) 51 (43.2)
Colposcopic Impression
 Low-Grade 266 (89.3) 111 (94.9) 96 (81.4) < 0.01
 High-Grade 25 (8.4) 1 (0.9) 20 (17.0)
 Missing 7 (2.4) 5 (4.3) 2 (1.7)
  1. *Fisher’s Exact to compare persistence vs. clearance
  2. aViral load was categorized as detectable and undetectable according to the Rwanda guidelines where all viral load results of less than 200 viral copies/mL of blood
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