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Table 1 General participant characteristics and results by persistence vs. clearance of hrHPV by AmpFire

From: Type-specific persistence, clearance and incidence of high-risk HPV among screen-positive Rwandan women living with HIV

Characteristic

All Women

Clearance

Persistence

p*

n = 298

n = 117

n = 118

n (%col)

n (%col)

n (%col)

Age Group (Years)

 30–33

70 (23.5)

31 (26.5)

23 (19.5)

0.19

 34–36

60 (20.1)

25 (21.4)

28 (23.7)

 37–42

82 (27.5)

35 (29.9)

28 (23.7)

 43–54

85 (28.5)

26 (22.2)

39 (33.0)

 Missing

1 (0.3)

0 (0.0)

0 (0.0)

Age at Sexual Initiation (Years)

  < 18

180 (60.4)

51 (43.6)

42 (35.6)

0.21

  ≥ 18

118 (39.6)

66 (56.4)

76 (64.4)

Number of Sexual Partners (Lifetime)

  ≤ 5

245 (82.2)

94 (80.3)

98 (83.1)

0.59

  ≥ 6

53 (17.8)

23 (19.7)

20 (16.9)

Number of Sexual Partners (Last 6 Months)

  ≤ 5

285 (95.6)

111 (94.8)

113 (95.8)

0.90

  ≥ 6

8 (2.7)

3 (2.6)

3 (2.5)

 Missing

5 (1.7)

3 (2.6)

2 (1.7)

Number of Children

  < 5

230 (77.2)

90 (76.9)

92 (78.0)

0.85

  ≥ 5

68 (22.8)

27 (23.1)

26 (22.0)

CD4 (per mm3) (Screening Visit)

  ≥ 500 (ref)

146 (49.0)

62 (53.0)

49 (41.5)

0.34

 350–499

64 (21.5)

23 (19.7

26 (22.0)

 200–349

48 (16.1)

17 (14.5)

22 (18.6)

  < 200

25 (8.4)

8 (6.8)

15 (12.7)

 Missing

15 (5.0)

7 (6.0)

6 (5.1)

On Anti-Retrovirals

 No

3 (1.0)

1 (0.9)

2 (1.7)

1.00

 Yes

293 (98.3)

115 (99.3)

115 (97.5)

 Missing

2 (0.7)

1 (0.9)

1 (0.9)

HIV Viral Loada (Screening Visit)

 Undetectable

236 (79.2)

91 (77.8)

92 (80.0)

0.04

 Detectable

28 (9.4)

9 (7.7)

18 (15.3)

 Missing

34 (11.4)

17 (14.5)

8 (6.8)

Time between Screening and Colposcopy Visits (Days)

 197–489

72 (24.2)

27 (23.1)

40 (33.9)

0.06

 490–649

73 (24.5)

39 (33.3)

22 (18.6)

 650–820

74 (24.8)

22 (18.8)

29 (24.6)

 821–1161

73 (24.5)

25 (21.4)

25 (21.9)

 Missing

6 (2.0)

4 (3.4)

2 (1.7)

VIA Result (Screening Visit)

 Negative

228 (76.5)

100 (85.5)

104 (88.1)

0.50

 Positive

68 (22.8)

15 (12.8)

14 (11.9)

 Missing

2 (0.7)

2 (1.7)

0 (0.0)

Number of hrHPV Types (Screening Visit)

 0

63 (21.1)

–

–

1.00

 1

133 (44.6)

66 (56.4)

67 (56.8)

  ≥ 2

102 (34.2)

51 (43.6)

51 (43.2)

Colposcopic Impression

 Low-Grade

266 (89.3)

111 (94.9)

96 (81.4)

< 0.01

 High-Grade

25 (8.4)

1 (0.9)

20 (17.0)

 Missing

7 (2.4)

5 (4.3)

2 (1.7)

  1. *Fisher’s Exact to compare persistence vs. clearance
  2. aViral load was categorized as detectable and undetectable according to the Rwanda guidelines where all viral load results of less than 200 viral copies/mL of blood