Table 1 Social-behavioral and clinical characteristics of anal HSIL and cancer cases compared with non-HSIL or cancer subjects (N = 112 individuals) from the 1917 clinic
|
Anal HSIL (N = 79) | Anal cancer (N = 43) | Anal HSIL and cancer free (N = 4367) | |
|---|---|---|---|
| Race | |||
| Blacks | 42 (53.2) | 18 (41.9)‡ | 2618 (60.0) |
| Whites | 36 (45.6) | 24 (55.8)‡ | 1575 (36.0) |
| Others | 1 (1.2.) | 1 (2.3) ‡ | 174 (4.0) |
| Gender | |||
| Men | 76 (96.0)* | 43 (100)* | 3315 (75.9) |
| Women | 3 (4.0)* | 0 (0)* | 1028 (23.5) |
| Transgender individuals | 0 (0)* | 0 (0) | 24 (0.50) |
| Self-reported sexual risks | |||
| Heterosexual | 5 (6.5)* | 7 (17.1)‡ | 1826 (43.5) |
| MSM | 72 (93.5)* | 34 (82.9)‡ | 2360 (56.2) |
| Others | 0 (0)* | 0 (0) ‡ | 11 (0.30) |
| Median age at HIV diagnoses (years) | 28.8 (24.6–37.7)‡ | 31.7 (25.6–38.8) | 32.9 (26.4–54.0) |
| Median age at study enrollment (years) | 38.4 (27.3–46.7) | 44.9 (40.7–50.9)‡ | 40.9 (31.8–59.1) |
| Median age at anal HSIL, cancer, or last clinical visit (years)‡ | 43.8 (31.8–54.2) | 51.4 (46.9–54.6) | 46.1 (36.2–54.6) |
| Nadir CD4 count (cells/μL) | |||
| < 200 | 36 (45.6) | 27 (62.8)‡ | 1699 (38.9) |
| 200–500 | 28 (35.4) | 11 (25.6)‡ | 1819 (41.7) |
| > 500 | 15 (19.0) | 5 (11.6)‡ | 849 (19.4) |
| Median CD4 count (cells/μL) | |||
| < 200 | 18 (22.8)‡ | 14 (32.6)* | 612 (14.0) |
| 200–500 | 28 (35.4)‡ | 19 (44.2)* | 1606 (36.8) |
| > 500 | 33 (41.8)‡ | 10 (23.3)* | 2149 (49.2) |
| Highest VL (copies/mL) | |||
| < 50 (undetectable) | 13 (16.5) | 6 (14.0) | 430 (9.9) |
| > 50 (detectable) | 66 (83.5) | 37 (86.0) | 393 (90.1) |
| Median VL (copies/mL) | |||
| < 50 (undetectable) | 44 (55.7) | 21 (48.8) | 2641 (60.5) |
| > 50 (detectable) | 35 (44.3) | 22 (51.2) | 1726 (39.5) |
| Ever received anal/rectal Pap 1 year before diagnosis | |||
| Yes | 40 (50.6) | 14 (32.6) | |
| No | 39 (49.4) | 29 (67.4) * | |
| Marital status | N = 78 | N = 43 | N = 4240 |
| Married/life partner | 3 (3.9)‡ | 9 (20.9)‡ | 609 (14.3) |
| Divorced/separated | 2 (2.5)‡ | 3 (7.0)‡ | 395 (9.3) |
| Single | 73 (93.6)‡ | 29 (67.4)‡ | 3111 (73.4) |
| Widowed | 0 (0)‡ | 2 (4.7)‡ | 125 (3.0) |
| Employment status | N = 73 | N = 38 | N = 3197 |
| Unemployed | 13 (17.8) | 5 (13.2)‡ | 660 (20.7) |
| Disabled | 23 (31.5) | 21 (55.3)‡ | 866 (27.1) |
| Employed | 31 (42.5) | 9 (23.7)‡ | 1417 (44.3) |
| Retired | 4 (5.5) | 2 (5.3)‡ | 208 (6.5) |
| Student | 2 (2.7) | 1 (2.5)‡ | 46 (1.4) |