Table 1 Social-behavioral and clinical characteristics of anal HSIL and cancer cases compared with non-HSIL or cancer subjects (N = 112 individuals) from the 1917 clinic

Race

 Blacks

42 (53.2)

18 (41.9)^‡

2618 (60.0)

 Whites

36 (45.6)

24 (55.8)^‡

1575 (36.0)

 Others

1 (1.2.)

1 (2.3) ^‡

174 (4.0)

Gender

 Men

76 (96.0)*

43 (100)*

3315 (75.9)

 Women

3 (4.0)*

0 (0)*

1028 (23.5)

 Transgender individuals

0 (0)*

0 (0)

24 (0.50)

Self-reported sexual risks

 Heterosexual

5 (6.5)*

7 (17.1)^‡

1826 (43.5)

 MSM

72 (93.5)*

34 (82.9)^‡

2360 (56.2)

 Others

0 (0)*

0 (0) ^‡

11 (0.30)

Median age at HIV diagnoses (years)

28.8 (24.6–37.7)^‡

31.7 (25.6–38.8)

32.9 (26.4–54.0)

Median age at study enrollment (years)

38.4 (27.3–46.7)

44.9 (40.7–50.9)^‡

40.9 (31.8–59.1)

Median age at anal HSIL, cancer, or last clinical visit (years)^‡

43.8 (31.8–54.2)

51.4 (46.9–54.6)

46.1 (36.2–54.6)

Nadir CD4 count (cells/μL)

  < 200

36 (45.6)

27 (62.8)^‡

1699 (38.9)

 200–500

28 (35.4)

11 (25.6)^‡

1819 (41.7)

  > 500

15 (19.0)

5 (11.6)^‡

849 (19.4)

Median CD4 count (cells/μL)

  < 200

18 (22.8)^‡

14 (32.6)*

612 (14.0)

 200–500

28 (35.4)^‡

19 (44.2)*

1606 (36.8)

  > 500

33 (41.8)^‡

10 (23.3)*

2149 (49.2)

Highest VL (copies/mL)

  < 50 (undetectable)

13 (16.5)

6 (14.0)

430 (9.9)

  > 50 (detectable)

66 (83.5)

37 (86.0)

393 (90.1)

Median VL (copies/mL)

  < 50 (undetectable)

44 (55.7)

21 (48.8)

2641 (60.5)

  > 50 (detectable)

35 (44.3)

22 (51.2)

1726 (39.5)

Ever received anal/rectal Pap 1 year before diagnosis

 Yes

40 (50.6)

14 (32.6)

 No

39 (49.4)

29 (67.4) *

Marital status

N = 78

N = 43

N = 4240

 Married/life partner

3 (3.9)^‡

9 (20.9)^‡

609 (14.3)

 Divorced/separated

2 (2.5)^‡

3 (7.0)^‡

395 (9.3)

 Single

73 (93.6)^‡

29 (67.4)^‡

3111 (73.4)

 Widowed

0 (0)^‡

2 (4.7)^‡

125 (3.0)

Employment status

N = 73

N = 38

N = 3197

 Unemployed

13 (17.8)

5 (13.2)^‡

660 (20.7)

 Disabled

23 (31.5)

21 (55.3)^‡

866 (27.1)

 Employed

31 (42.5)

9 (23.7)^‡

1417 (44.3)

 Retired

4 (5.5)

2 (5.3)^‡

208 (6.5)

 Student

2 (2.7)

1 (2.5)^‡

46 (1.4)