Fig. 5

Low NSD1, NSD2, or NSD3 expression is strongly associated with reduced survival in patients with HPV+ but not HPV- HNSCC. Overall survival of patients grouped by high, mid, or low expression of NSD1, NSD2, or NSD3 in the HPV+ (a) and HPV- (b) HNSCC cohorts. Comparison between groups were calculated with the 2-sided log-rank test (p value) and multiple comparisons corrected with the Benjamini–Hochberg method utilizing an FDR threshold of 10% (q value). Numbers in brackets indicate the number of samples included in each expression group