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Fig. 4 | Infectious Agents and Cancer

Fig. 4

From: Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis

Fig. 4

T-cell infiltration is not correlated with NSD1 expression in HPV+ HNSCC, but is weakly correlated in HPV- HNSCC. A previously reported 13 gene T-cell transcript signature was calculated for each sample in the TCGA HNSCC cohort and compared pairwise with normalized RNA-seq data for NSD1, NSD2, and NSD3 for HPV+ (a) and HPV- (b) HNSCC samples. For each NSD paralog, the correlation with the T-cell transcript signature was calculated by Spearman’s Rho analysis

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