Fig. 5
From: HPV-mediated down-regulation of NOD1 inhibits apoptosis in cervical cancer
The activation of NOD1 increased CHX-induced apoptosis. NOD1 expression increased in SiHa cells treated with iE-DAP (**P < 0.005, ***P < 0.0001) (a). The NOD1 activation enhanced CHX-induced apoptosis. HPV16-positive SiHa cells were treated with iE-DAP in the presence or absence of CHX. Cell viability was measured by flow cytometry. The apoptosis of SiHa cells increased significantly in the presence of CHX (P < 0.005) (b)