Fig. 4
From: HPV-mediated down-regulation of NOD1 inhibits apoptosis in cervical cancer
HPV oncoproteins down-regulated the expression of NOD1 and RIP2 in C33A cells. NOD1 expression was down-regulated in the cancer cells transfected with E6- or E7-expressing plasmids detected by immunocytochemistry (a), Western blot (b), and RT-PCR (c). RIP2 mRNA expression was down-regulated in the cancer cells transfected with E6- or E7-expressing plasmids detected by RT-PCR (d). BLANK, without plasmid, VECT, empty vector, E6, E6-expressing plasmids, and E7, E7-expressing plasmids