Fig. 4
From: Host proteome linked to HPV E7-mediated specific gene hypermethylation in cancer pathways
Pathway enrichment of overall identified proteins, enrichment heatmap of down-regulated proteins and expression mapping of gene candidates heatmap. Down-regulated proteins were annotated against cancer pathways for seeking for gene candidates to further mRNA expression and DNA methylation analysis (a). Protein expression across several cell types and tissues, gene candidates were annotated against protein expression pattern from Human protein atlas database. Apparently, selected proteins relatively less express in cancer cell type and tissues (b)