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Table 4 The sensitivity and specificity for ≥CIN 2 for the Cobas and SeqHPV assays

From: An evaluation of solid versus liquid transport media for high-risk HPV detection and cervical cancer screening on self-collected specimens

HPV tests

Sensitivity (95%CI)

P value

Specificity (95% CI)

P value

NPV ((95% CI)

Cobas--SL

95.07 (89.72, 97.82)

-

87.35 (86.68, 87.98)

-

99.92 (99.83,99.97)

Cobas—SC

94.37 (88.83, 97.36)

1.0

88.74 (88.11, 89.34)

<0.001

99.91 (99.82,99.96)

Seq--SL

96.48 (91.55, 98.70)

-

89.53 (88.92, 90.11)

-

99.95 (99.87,99.98)

Seq—SC

95.77 (90.63, 98.27)

1.0

89.54 (88.93, 90.12)

0.89

99.93 (99.85,99.97)

  1. Note: ≥ CIN2 Cervical intraepithelial neoplasia 2 or higher, 95%CI 95% confidence interval
  2. The comparison of solid vs. liquid transport media for detecting HR-HPV in vaginal self-collected specimens were calculated using the McNemar’s Chi-square test
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Infectious Agents and Cancer

ISSN: 1750-9378

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