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Table 4 The sensitivity and specificity for ≥CIN 2 for the Cobas and SeqHPV assays

From: An evaluation of solid versus liquid transport media for high-risk HPV detection and cervical cancer screening on self-collected specimens

HPV tests Sensitivity (95%CI) P value Specificity (95% CI) P value NPV ((95% CI)
Cobas--SL 95.07 (89.72, 97.82) - 87.35 (86.68, 87.98) - 99.92 (99.83,99.97)
Cobas—SC 94.37 (88.83, 97.36) 1.0 88.74 (88.11, 89.34) <0.001 99.91 (99.82,99.96)
Seq--SL 96.48 (91.55, 98.70) - 89.53 (88.92, 90.11) - 99.95 (99.87,99.98)
Seq—SC 95.77 (90.63, 98.27) 1.0 89.54 (88.93, 90.12) 0.89 99.93 (99.85,99.97)
  1. Note: ≥ CIN2 Cervical intraepithelial neoplasia 2 or higher, 95%CI 95% confidence interval
  2. The comparison of solid vs. liquid transport media for detecting HR-HPV in vaginal self-collected specimens were calculated using the McNemar’s Chi-square test