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Table 3 Study characteristics of studies investigating the prognostic relevance of HPV-16 and HPV-18

From: Prognostic implication of human papillomavirus types in cervical cancer patients: a systematic review and meta-analysis

Author Year Country Total number of patients Mean age Clinical stage Treatment Number of patients with HPV-16 positive Number of patients with HPV-18 positive Median DFS Median PFS Median OS
Mi Chen 2019 China 131 29–61 I-III adjuvant radiation 88 19 HR: 1.13, 95% CI = 0.78–1.64 NA HR: 1.39, 95% CI = 1.14–1.69
Yuanyuan Wang 2018 China 232 NA I-III adjuvant radiation 108 19 NA Not significant HR: 2.17, 95% CI = 1.20–3.92
Ruihong Lan 2017 China 40 40.21 II-III adjuvant radiation 22 10 NA NA HR: 1.15, 95% CI = 1.01–1.31