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Table 3 Study characteristics of studies investigating the prognostic relevance of HPV-16 and HPV-18

From: Prognostic implication of human papillomavirus types in cervical cancer patients: a systematic review and meta-analysis

Author

Year

Country

Total number of patients

Mean age

Clinical stage

Treatment

Number of patients with HPV-16 positive

Number of patients with HPV-18 positive

Median DFS

Median PFS

Median OS

Mi Chen

2019

China

131

29–61

I-III

adjuvant radiation

88

19

HR: 1.13, 95% CI = 0.78–1.64

NA

HR: 1.39, 95% CI = 1.14–1.69

Yuanyuan Wang

2018

China

232

NA

I-III

adjuvant radiation

108

19

NA

Not significant

HR: 2.17, 95% CI = 1.20–3.92

Ruihong Lan

2017

China

40

40.21

II-III

adjuvant radiation

22

10

NA

NA

HR: 1.15, 95% CI = 1.01–1.31