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Table 2 Final diagnosis and resection margin status after LEEP, excluding cases lost to follow-up (n = 381)

From: Loop electrosurgical excision procedure combined with cold coagulation for cervical intraepithelial neoplasia and adenocarcinoma in-situ: a feasible treatment with a low risk of residual/recurrent disease

Diagnosis after-LEEP, n Positive RM, n (%) Residual disease, n (%)
CIN1, 70 0 0
CIN2/3, 290 44 (15.2) 1 (0.3)
 Endocervix 25a  1 (CIN3, LEEP at 4 mo)
 Exocervix 18a  0
 Both margins 1a  0
AIS, 5 1 (20.0) 0
 Endocervix 1b  0
 Exocervix 0  
 Both margins 0  
Microinvasive SCC, 13 8 (61.5) 2 (15.4)
 Endocervix 5  1b (microinvasive SCC)
 Exocervix 0  
 Both margins 3  1b (invasive SCC)
Invasive SCC, 3 3 (100.0) 0
 Endocervix 2c  0
 Exocervix 0  
Both margins 1c  0
  1. LEEP loop electrosurgical excision procedure, RM resection margin, CIN cervical intraepithelial neoplasia, AIS adenocarcinoma in-situ, SCC squamous cell carcinoma
  2. afollow-up without additional LEEP (pap smear, HPV DNA testing and endocervical curettage at 4–6 months);
  3. bhysterectomy
  4. cradical hysterectomy, radical trachelectomy