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Table 2 Final diagnosis and resection margin status after LEEP, excluding cases lost to follow-up (n = 381)

From: Loop electrosurgical excision procedure combined with cold coagulation for cervical intraepithelial neoplasia and adenocarcinoma in-situ: a feasible treatment with a low risk of residual/recurrent disease

Diagnosis after-LEEP, n

Positive RM, n (%)

Residual disease, n (%)

CIN1, 70

0

0

CIN2/3, 290

44 (15.2)

1 (0.3)

 Endocervix 25a

 1 (CIN3, LEEP at 4 mo)

 Exocervix 18a

 0

 Both margins 1a

 0

AIS, 5

1 (20.0)

0

 Endocervix 1b

 0

 Exocervix 0

 

 Both margins 0

 

Microinvasive SCC, 13

8 (61.5)

2 (15.4)

 Endocervix 5

 1b (microinvasive SCC)

 Exocervix 0

 

 Both margins 3

 1b (invasive SCC)

Invasive SCC, 3

3 (100.0)

0

 Endocervix 2c

 0

 Exocervix 0

 

Both margins 1c

 0

  1. LEEP loop electrosurgical excision procedure, RM resection margin, CIN cervical intraepithelial neoplasia, AIS adenocarcinoma in-situ, SCC squamous cell carcinoma
  2. afollow-up without additional LEEP (pap smear, HPV DNA testing and endocervical curettage at 4–6 months);
  3. bhysterectomy
  4. cradical hysterectomy, radical trachelectomy