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Fig. 4 | Infectious Agents and Cancer

Fig. 4

From: A study of the mechanism of lncRNA-CR594175 in regulating proliferation and invasion of hepatocellular carcinoma cells in vivo and in vitro

Fig. 4

Effects of lncRNA-CR594175 depletion on proliferation and invasion of HCC cells and In vivo tumor suppression. a Cell proliferation activity assay. HepG2 were infected with the indicated lentivirus and then seeded to 96-well plates and used for the detection of cell viability at the 0,24,48 and 72 h. The x-coordinate represents proliferation at different time points and the y-coordinate represents the absorbance at 490 nm. b Cell invasion assay: HepG2 cells 48 h after infection with the indicated lentiviruses; representative images of cells that seeded into the upper chamber of a transwell and passed through the basement membrane. c Growth curves of tumor in vivo. The x-coordinate represents the period of virus injection and the y-coordinate represents the tumor volume (mm3). The formula for calculating the tumor volume was: V = 0.5 × a × b × b, where a and b are the long and short diameters of the tumor. The number of animals in one group was 12 (n = 12). ** p < 0.01, *p < 0.05, t-test, data are expressed as the means ± SD

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