Association of human papilloma virus (HPV) infection with oncological outcomes in urothelial bladder cancer

Table 1 The association between patient characteristics and HPV status of patients

	Group	HPV		p-value
	Group	Negative (%)	Positive (%)	p-value
Sex	Male	64 (78)	21 (87.5)	0.393^a
Sex	Female	18 (22)	3 (12.5)	0.393^a
Cigarette smoker	Smoker	59 (72)	22 (91.7)	0.045^b
Cigarette smoker	Non-smoker	23 (28)	2 (8.3)	0.045^b
Family history of cancer	Positive	36 (43.9)	11 (45.8)	0.867^b
Family history of cancer	Negative	46 (56.1)	13 (54.2)	0.867^b
Tumor grade	Low grade	52 (63.4)	7 (29.2)	0.003^b
Tumor grade	High grade	30 (36.6)	17 (70.8)	0.003^b
Tumor stage	Ta	45 (54.9)	5 (20.8)	< 0.0001^a
	T1	10 (12.2)	3 (12.5)
	T2	26 (31.7)	7 (29.2)
	T3-T4	1 (1.2)	9 (37.5)
Muscle invasion	Positive	27 (32.9)	16 (66.7)	0.003^b
Muscle invasion	Negative	55 (67.1)	8 (33.3)	0.003^b
Recurrence after 18 month	Positive	37 (45.1)	24 (100)	< 0.0001^b
Recurrence after 18 month	Negative	45 (54.9)	0 (0)	< 0.0001^b
^a Fisher exact test; ^b Chi square test

ISSN: 1750-9378