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Table 1 Characteristics of studies included in the current study

From: Bovine Leukemia virus (BLV) and risk of breast cancer: a systematic review and meta-analysis of case-control studies

study Publication year Sample collection date country continent Study-design Sample type Detection target Case Case positive Control Control positive Detection method Age control Age case NOS score ref
Giovanna 2013 Since 2006 Colombia South America Case–control FFPE Gag 53 19 53 24 PCR 52.2 46.4 8 [14]
Schwingel 2019 2015–2017 Brazil South America Case–control FFPE Tax 72 22 72 10 Nested PCR 38 52.5 9 [15]
Buehring 2007 NR US North America Case–control FFPE Tax 110 65 103 30 In situ PCR NR NR 9 [16]
Buehring 2015 2002–2008 US North America Case–control FFPE Tax 114 67 104 30 In situ PCR 48.7 55.9 9 [17]
Baltzell 2017 2009–2011 US North America Case–control FFPE Tax 61 35 103 20 In situ PCR 54.4 54.59 9 [18]
Buehring 2017 1995–2010 Australia ocenia Case–control FFPE Tax 50 40 46 19 In situ PCR 49.59 55.08 9 [12]
Lawson and Glenn 2017 NR Australia ocenia Case–control FFPE Tax 22 20 17 6 In situ PCR 36.4 56.1 8 [19]
Khalilian 2019 2017–2018 Iran Middle East Case–control FFPE and Blood Tax 172 52 200 60 In situ PCR 47.5 53 9 [11]
Khalilian 2019 2017–2018 Iran Middle east Case–control FFPE and Blood Gag 172 14 200 16 Nested PCR 47.5 53 8 [11]
  1. FFPE Formalin-fixed paraffin-embedded, PCR Polymerase chain reaction, NOS Newcastle- Ottawa assessment scale