Table 7 Univariate and multivariate analyses of the risk factors for uterine corpus invasion in stage I-IIA cervical cancer
Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
HPV58 positivity | 3.652 | 1.060-12.584 | 0.040 | 3.985 | 1.066-14.893 | 0.040 |
Age<50 years old | 1.365 | 0.672-2.774 | 0.390 | / | / | / |
Non-SCC | 2.426 | 0.298-19.744 | 0.408 | / | / | / |
Moderately/well differentiated | 0.484 | 0.235-0.996 | 0.049 | 0.531 | 0.239-1.180 | 0.120 |
Maximum diameter>4 cm | 1.834 | 0.885-3.799 | 0.103 | / | / | / |
Depth of stromal invasion | 2.494 | 1.569-3.965 | 0.000 | 2.039 | 1.205-3.452 | 0.008 |
Lymph node metastasis (+) | 0.280 | 0.132-0.591 | 0.000 | 0.636 | 0.266-1.521 | 0.309 |
LVSI (+) | 0.236 | 0.110-0.504 | 0.000 | 0.386 | 0.164-0.909 | 0.029 |
Parametrial invasion (+) | 0.383 | 0.118-1.245 | 0.111 | / | / | / |
Bladder invasion (+) | 0.162 | 0.026-1.007 | 0.051 | / | / | / |
Rectal invasion (+) | 0.514 | 0.045-5.814 | 0.590 | / | / | / |
Vaginal invasion (+) | 0.327 | 0.115-0.923 | 0.035 | 0.523 | 0.166-1.645 | 0.267 |