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Table 3 CTNNB1 mutation in HCC cases according to demographic and pathological characteristics

From: Investigation of CTNNB1 gene mutations and expression in hepatocellular carcinoma and cirrhosis in association with hepatitis B virus infection

Characteristics

CTNN mutation N (%)

P

Male

14 (17.7)

0.575

Female

5 (19.2)

 

Age

 40 >

1 (12.5)

0.034a

 40–50

1 (9.1)

 

 51–60

4 (16.6)

 

  > 60

13 (21)

 

Differentiation

 Well

9 (28.1)

0.097b

 Moderate

5 (16.7)

 

 Poorly

4 (15.4)

 

 Un-known

1 (5.9)

 

LC-HCC

 Yes

4 (14.8)

0.423

 No

15 (19.2)

 
  1. aThe frequency of mutations was significantly increased toward aging, bThe rate of mutations in well differentiated tumors was higher than others
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Infectious Agents and Cancer

ISSN: 1750-9378

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