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Table 3 Distribution of hr-HPV genotypes and histological results among hr-HPV-positive/cytology-negative women

From: Risk of cervical lesions in high-risk HPV positive women with normal cytology: a retrospective single-center study in China

HPV Type(s) Histological Results
TOTAL NORMAL(n,%) LSIL(n,%) HSIL(n,%) CA(n,%) HSIL+(n,%) HSIL+ OR(95% CI)
HPV infection(s) with 16 and/or 18
 HPV16 1047 522 (49.86) 169 (16.14) 325 (31.04) 31 (2.96) 356 (34.00)  
 HPV18 270 175 (64.81) 61 (22.59) 30 (11.11) 4 (1.48) 34 (12.59)  
 16 + other(s)a 492 213 (43.29) 105 (21.34) 166 (33.74) 8 (1.63) 174 (35.37)  
 18 + other(s)a 120 56 (46.67) 38 (31.67) 26 (21.67) 0 (0.00) 26 (21.67)  
 16 + 18 + other(s) a 79 30 (37.97) 17 (21.52) 31 (39.24) 1 (1.27) 32 (40.51)  
No. of hr HPV type(s) without HPV16 or 18
 1 typeb 839 558 (66.51) 178 (21.22) 101 (12.04) 2 (0.24) 103 (12.28) 1
 2 typesc 192 118 (61.46) 35 (18.23) 39 (20.31) 0 (0.00) 39 (20.31) 1.821 (1.212–2.738)
  ≥ 3 typesd 40 19 (47.50) 6 (15.00) 15 (37.50) 0 (0.00) 15 (37.50) 4.287 (2.188–8.400)
Unknown type(s)
 HC2e 1548 984 (63.57) 300 (19.38) 247 (15.96) 17 (1.10) 264 (17.05)  
 12 hr-HPVf 1253 851 (67.92) 246 (19.63) 156 (12.45) 0 (0.00) 156 (12.45)  
Total
 Ng 5880 3526 (59.97) 1155 (19.64) 1136 (19.32) 63 (1.07) 1199 (20.39)  
  1. HPV human papillomavirus
  2. hr-HPV high-risk human papillomavirus
  3. LSIL low-grade squamous intraepithelial lesion
  4. HSIL high-grade squamous intraepithelial lesion
  5. CA cervical cancer
  6. HSIL+ high-grade squamous intraepithelial lesion or worse
  7. OR odds ratio
  8. CI confidence interval
  9. a=hr-HPV genotypes except HPV16 or 18
  10. b= single hr-HPV infection without HPV16 or 18
  11. c= double hr-HPV infections HPV16 or 18
  12. d= triple or more hr-HPV infections HPV16 or 18
  13. e= infection(s) with a pool of 12 other hr-HPV types (including HPV 31,33,35,39,45,51,52,56,58,59,66 and 68) that did not know the specific type of HPV (from Cobas 4800 HPV test)
  14. f=13 hr-HPV types (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68) tested by Hybrid Capture 2(HC2)High-Risk HPV DNA Test
  15. g=The total number of people with hr-HPV positive in the corresponding histological results groups