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Table 1 Prevalence of Xq21.33 Detection in African Women with or without Breast Cancer

From: Is the HERV-K HML-2 Xq21.33, an endogenous retrovirus mutated by gene conversion of chromosome X in a subset of African populations, associated with human breast cancer?

AgeBrC
No Xq21.33
BrC Xq21.33No BrC
No Xq21.33
No BrC Xq21.33(chi square test, p value)
15–190010 
20–242031
25–29120253
30–34174315
35–39384384
40–44364415
Total pre-menopausal1051213918X2 = 0.100
p < 0.3757 (ns)
 45–49233263 
 50–5427880
 55–59162111
 60–647150
 65–696000
 70–741000
 75–793000
 80–840000
 85–890100
Total post-menopausal8315504X2 = 1.986
p < 0.079 (ns)
Age unknown1 8  
Total1892719722 
  1. Detection of HK2 Xq21.33 provirus in the DNA of BrC and control women (No BrC) in populations from African ancestry. The P values show the statistical significance difference of Xq21.33 virus detection between pre-menopausal and post-menopausal women with and without BrC. The statistical test Chi-square without Yates correction was used. The X2 and p values are indicated. There is no statistical difference between the prevalence of Xq21.33 in the pre-menopausal women but the prevalence of Xq21.33 in post-menopausal women is approximately double that in women without breast cancer but this is also not statistically different at a p value of <.05