Table 2 Prognostic factors for RFS by Cox proportional hazards regression model
Factors | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Gender | 1.72 (1.10–2.69) | 0.016 | 1.63 (0.97–2.72) | 0.061 |
Age | 0.88 (0.62–1.23) | 0.466 |  |  |
Diabetes mellitus | 1.37 (0.93–2.01) | 0.108 |  |  |
High blood pressure | 1.03 (0.71–1.49) | 0.866 |  |  |
History of smoking | 1.51 (1.08–2.09) | 0.014 | 1.11 (0.76–1.63) | 0.579 |
History of drinking | 1.22 (0.86–1.72) | 0.248 |  |  |
Cirrhosis | 1.28 (0.85–1.92) | 0.222 |  |  |
Child-Pugh class | 1.27 (0.90–1.78) | 0.166 |  |  |
Antiviral therapy | 0.77 (0.55–1.08) | 0.135 |  |  |
Tumor number | 2.36 (1.68–3.32) | < 0.0001 | 1.98 (1.38–2.85) | < 0.0001 |
Tumor size | 1.60 (1.15–2.24) | 0.005 | 0.93 (0.61–1.41) | 0.748 |
Ablation method | 0.90 (0.74–1.10) | 0.341 |  |  |
Etiology | 1.71 (0.89–1.53) | 0.250 |  |  |
AFP | 1.44 (1.13–1.82) | 0.002 | 1.29 (1.01–1.66) | 0.041 |
Viral load | 1.00 (0.75–1.31) | 0.291 |  |  |
ALT(U/L) | 1.00 (0.99–1.01) | 0.237 |  |  |
AST(U/L) | 1.01 (0.99–1.02) | 0.062 |  |  |
Total serum bilirubin (mg/dL) | 1.00 (0.99–1.02) | 0.369 |  |  |
Neutrophil count (10^9/L) | 1.08 (0.98–1.19) | 0.113 |  |  |
Lymphocyte count (10^9/L) | 0.99 (0.75–1.31) | 0.970 |  |  |
Platelet count (10^9/L) | 1.00 (0.99–1.00) | 0.147 |  |  |
Albumin | 0.95 (0.91–0.98) | 0.012 | 0.97 (0.92–1.01) | 0.193 |
Globulin | 1.03 (1.00–1.06) | 0.015 | 1.01 (0.99–1.05) | 0.206 |
Fibrinogen (mg/dL) | 1.32 (1.12–1.55) | 0.001 | 1.23 (1.00–1.50) | 0.042 |
GPR | 1.27 (1.13–1.41) | < 0.0001 | 1.15 (1.00–1.33) | 0.048 |