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Table 2 Comparison of serological indices, inflammation grade and fibrosis grade in HBV DNA negative and positive hepatitis B patients after 12-month follow up

From: Pathological changes of liver one year later in CHB patients with negative HBV DNA

Test IndexGroup AGroup B
Baseline level12 months laterBaseline level12 months later
ALT(U/L)37.77 ± 41.7430.21 ± 32.3740.77 ± 34.7251.08 ± 47.36@
AST(U/L)30.41 ± 20.9731.74 ± 35.1433.92 ± 17.1743.92 ± 35.53
TBIL (μmol/L)14.73 ± 6.0914.78 ± 5.9810.92 ± 2.76#11.55 ± 3.65
DBIL (μmol/L)4.70 ± 4.694.53 ± 1.982.90 ± 1.11#3.25 ± 1.30@
ALB(g/L)47.71 ± 3.6646.22 ± 3.12*46.37 ± 5.1044.58 ± 6.14
GLB(g/L)27.49 ± 4.5128.17 ± 4.1727.07 ± 4.8628.79 ± 4.98
ALP(U/L)71.09 ± 23.6267.75 ± 18.8567.54 ± 23.4969.31 ± 23.36
γ-GT (U/L)30.68 ± 29.5629.34 ± 23.5924.08 ± 20.5626.92 ± 21.25
PT(s)11.83 ± 0.9211.23 ± 0.89*11.29 ± 0.8210.95 ± 0.92
PTA(%)94.34 ± 10.15107.89 ± 9.58*98.90 ± 8.64113.06 ± 16.98&
WBC(10E9/L)5.36 ± 1.365.87 ± 1.786.18 ± 1.826.60 ± 2.43
PLT(10E9/L)158.68 ± 55.02159.78 ± 45.61170.33 ± 48.66168.62 ± 36.71
AFP (ng/mL)4.05 ± 2.942.85 ± 1.63*3.60 ± 1.793.86 ± 3.85
Inflammation Grade1.42 ± 0.631.37 ± 0.591.00 ± 0.41#1.38 ± 0.51&
Fibrosis Stage1.38 ± 1.141.60 ± 1.050.85 ± 0.691.31 ± 0.85
HBeAg (Positive)!33 (41.77%)25 (31.65%)7 (53.85%)3 (23.08%)
  1. *P < 0.05 versus the value of the baseline level of group A
  2. &P < 0.05 versus the value of the baseline level of group B
  3. #P < 0.05 versus the value of the baseline level of group A
  4. @P < 0.05 versus the value of 12 months later of group A
  5. ! no. (%)