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Table 2 Selected groups of functions determined by GO in different gene samples represented in Fig. 1

From: Evolutionarily novel genes are expressed in transgenic fish tumors and their orthologs are involved in development of progressive traits in humans

GO functionsGene samples, studied with GO
343 Human orthologs of 296 fish TTRgrEEN genes296 fish TTRgrEEN genes with human orthologs113 fish TTRgrEEN genes without human orthologs
I Functions involved in developmental process
 Anatomical structure development
 52210
 Developmental growth
 181254
  Σ233464
II Functions involved in different aspects of transcription regulation
 Σ1117815
III Functions involved in different signaling pathways
 Σ1178621
IV Functions connected with immune system
 Σ5296
 Σ Σ51321946
  1. The total number of functions determined by Gene Ontology for 296 fish TTRgrEEN genes with human orthologs is 1813 and for 343 human orthologs is 6300. The 113 fish TTRgrEEN genes with no human orthologs have 465 functions. The total number of functions for each gene was summed, skipping the repeated annotation in GO from different evidence codes. The total number of functions for each gene sample is the sum of all functions of all genes from this sample