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Table 2 Selected groups of functions determined by GO in different gene samples represented in Fig. 1

From: Evolutionarily novel genes are expressed in transgenic fish tumors and their orthologs are involved in development of progressive traits in humans

GO functions

Gene samples, studied with GO

343 Human orthologs of 296 fish TTRgrEEN genes

296 fish TTRgrEEN genes with human orthologs

113 fish TTRgrEEN genes without human orthologs

I Functions involved in developmental process

 Anatomical structure development

 

52

21

0

 Developmental growth

 

181

25

4

  Σ

233

46

4

II Functions involved in different aspects of transcription regulation

 Σ

111

78

15

III Functions involved in different signaling pathways

 Σ

117

86

21

IV Functions connected with immune system

 Σ

52

9

6

 Σ Σ

513

219

46

  1. The total number of functions determined by Gene Ontology for 296 fish TTRgrEEN genes with human orthologs is 1813 and for 343 human orthologs is 6300. The 113 fish TTRgrEEN genes with no human orthologs have 465 functions. The total number of functions for each gene was summed, skipping the repeated annotation in GO from different evidence codes. The total number of functions for each gene sample is the sum of all functions of all genes from this sample